Early growth response 2 (Q21498352)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08152

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

early growth response transcription factors

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

3 references

14 February 2019

14 February 2019

Hoxb-2 transcriptional activation in rhombomeres 3 and 5 requires an evolutionarily conserved cis-acting element in addition to the Krox-20 binding site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

DNA-binding transcription factor activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

ISO

14 February 2019

A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

chromatin binding

1 reference

14 February 2019

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

1 reference

14 February 2019

protein binding

3 references

14 February 2019

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

PIASxbeta acts as an activator of Hoxb1 and is antagonized by Krox20 during hindbrain segmentation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

nucleic acid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

1 reference

14 February 2019

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

1 reference

14 February 2019

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

SUMO ligase activity

1 reference

14 February 2019

The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

cell component

cytoplasm

1 reference

14 February 2019

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

5 references

24 April 2018

24 April 2018

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

24 April 2018

PIASxbeta acts as an activator of Hoxb1 and is antagonized by Krox20 during hindbrain segmentation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

24 April 2018

Cell autonomy of the mouse claw paw mutation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

24 April 2018

A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

5 references

14 February 2019

14 February 2019

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

Cell autonomy of the mouse claw paw mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

cellular response to organic substance

biological process

1 reference

14 February 2019

Regulation of GATA-3 expression during CD4 lineage differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

regulation of transcription, DNA-templated

A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

24 April 2018

Nab proteins are essential for peripheral nervous system myelination

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

24 April 2018

rhombomere 3 development

1 reference

14 February 2019

Hoxa1 and Krox-20 synergize to control the development of rhombomere 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

brain segmentation

1 reference

14 February 2019

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

transcription by RNA polymerase II

1 reference

14 February 2019

Transcriptional regulation of adipogenesis by KLF4

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

protein sumoylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

1 reference

7 November 2018

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08152&geneProductId=UniProtKB:P08152

1 reference

24 April 2018

rhombomere 3 formation

1 reference

14 February 2019

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

rhombomere 5 formation

1 reference

14 February 2019

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

protein export from nucleus

1 reference

14 February 2019

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

learning or memory

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

skeletal muscle cell differentiation

1 reference

14 February 2019

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

myelination

3 references

14 February 2019

Nab proteins are essential for peripheral nervous system myelination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

regulation of neuronal synaptic plasticity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

facial nerve structural organization

1 reference

14 February 2019

Hoxa1 and Krox-20 synergize to control the development of rhombomere 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

regulation of ossification

1 reference

14 February 2019

Defective bone formation in Krox-20 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

motor neuron axon guidance

1 reference

14 February 2019

Hoxa1 and Krox-20 synergize to control the development of rhombomere 3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

fat cell differentiation

1 reference

14 February 2019

Transcriptional regulation of adipogenesis by KLF4

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

positive regulation of transcription by RNA polymerase II

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

14 February 2019

The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08152

has part(s)

Zinc finger C2H2-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08152

Early growth response, N-terminal

1 reference

InterPro Release 71.0