Estrogen related receptor, alpha (Q21494387)

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mammalian protein found in Mus musculus

Estrogen-related receptor alpha
nuclear receptor subfamily 3 group B member 1
estrogen receptor-like 1
Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1)
estrogen receptor related 1
Esrra
ERR-alpha
steroid hormone receptor ERR1

Language	Label	Description	Also known as
English	Estrogen related receptor, alpha	mammalian protein found in Mus musculus	Estrogen-related receptor alpha nuclear receptor subfamily 3 group B member 1 estrogen receptor-like 1 Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR-alpha) (Estrogen receptor-like 1) estrogen receptor related 1 Esrra ERR-alpha steroid hormone receptor ERR1

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Nuclear hormone receptor-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08580

Zinc finger, NHR/GATA-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08580

oestrogen-related receptor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08580

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method or standard

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

protein domain specific binding

determination method or standard

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

DNA-binding transcription factor activity

determination method or standard

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

zinc ion binding

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

2 references

16 July 2018

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08580&geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

metal ion binding

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method or standard

1 reference

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

steroid hormone receptor activity

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

2 references

16 July 2018

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08580&geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

steroid binding

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

sequence-specific DNA binding

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

protein binding

determination method or standard

1 reference

14 February 2019

Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor α (ERRα) cellular localization and inhibits its transcriptional activity.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

microtubule cytoskeleton

determination method or standard

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

intercellular bridge

determination method or standard

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

fibrillar center

determination method or standard

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

determination method or standard

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

determination method or standard

1 reference

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08580&geneProductId=UniProtKB:O08580

determination method or standard

determination method or standard

biological process

response to estradiol

determination method or standard

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

1 reference

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08580&geneProductId=UniProtKB:O08580

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

3 references

14 February 2019

PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

14 February 2019

Estrogen receptor-related receptor alpha (ERRalpha) regulates osteopontin expression through a non-canonical ERRalpha response element in a cell context-dependent manner

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

steroid hormone mediated signaling pathway

determination method or standard

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08580

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08580&geneProductId=UniProtKB:O08580

determination method or standard

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

diethylstilbestrol

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

nuclear hormone receptor-type zinc finger

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08580

Nuclear hormone receptor, ligand-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08580

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000025906

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000025906

ENSMUSP00000133916

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000133916

ENSMUSP00000134587

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000134587

ENSMUSP00000159237

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000159237

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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