Helicase, lymphoid specific (Q21433476)

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mammalian protein found in Mus musculus

• proliferation-associated SNF2-like protein
• lymphocyte-specific helicase
• Hells

edit

Language	Label	Description	Also known as
English	Helicase, lymphoid specific	mammalian protein found in Mus musculus	proliferation-associated SNF2-like protein lymphocyte-specific helicase Hells

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q60848

subclass of

protein

1 reference

stated in

UniProt

retrieved

19 January 2017

UniProt protein ID

Q60848

part of

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q60848

SNF2-like, N-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q60848

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SNF2-related, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q60848

encoded by

Hells

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q60848

molecular function

nucleotide binding

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

helicase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

chromatin binding

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

Lsh, an epigenetic guardian of repetitive elements

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IDA

hydrolase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

ATP binding

determination method or standard

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

protein binding

determination method or standard

IPI

2 references

retrieved

14 February 2019

stated in

Lsh is involved in de novo methylation of DNA

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IPI

retrieved

14 February 2019

stated in

Lsh controls Hox gene silencing during development

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IPI

cell component

pericentric heterochromatin

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IDA

chromosome, centromeric region

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IDA

nucleus

determination method or standard

IDA

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

retrieved

14 February 2019

stated in

Large-scale identification of mammalian proteins localized to nuclear sub-compartments

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IDA

biological process

pericentric heterochromatin assembly

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60848&geneProductId=UniProtKB:Q60848

determination method or standard

IEA

maintenance of DNA methylation

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

negative regulation of intrinsic apoptotic signaling pathway

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Lsh, a SNF2 family member, is required for normal murine development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

lymphocyte differentiation

determination method or standard

TAS

1 reference

retrieved

14 February 2019

stated in

Lsh, a SNF2 family member, is required for normal murine development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

TAS

negative regulation of apoptotic process

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Lsh, a SNF2 family member, is required for normal murine development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60848&geneProductId=UniProtKB:Q60848

determination method or standard

IEA

cell division

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

multicellular organism development

determination method or standard

IEA

IMP

2 references

retrieved

14 February 2019

stated in

Lsh, a SNF2 family member, is required for normal murine development

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

DNA methylation

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Lsh, a member of the SNF2 family, is required for genome-wide methylation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

DNA methylation-dependent heterochromatin assembly

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Lsh controls silencing of the imprinted Cdkn1c gene

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

lymphocyte proliferation

determination method or standard

IEP

1 reference

retrieved

14 February 2019

stated in

Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEP

urogenital system development

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Lsh, a SNF2 family member, is required for normal murine development

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IMP

cell cycle

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q60848

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEA

cellular response to leukemia inhibitory factor

determination method or standard

IEP

1 reference

retrieved

14 February 2019

stated in

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60848

determination method or standard

IEP

has part(s)

Helicase, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q60848

SNF2-related, N-terminal domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q60848

Helicase superfamily 1/2, ATP-binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q60848

Identifiers

RefSeq protein ID

NP_032260

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

15201

XP_006526762

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

15201

XP_006526763

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

15201

UniProt protein ID

Q60848

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q60848

Ensembl protein ID

ENSMUSP00000025965

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000025965

ENSMUSP00000116710

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000116710

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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