A-kinase anchoring protein 9 (Q21203032)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99996

ELK domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Pericentrin/AKAP-450 centrosomal targeting domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

transmembrane transporter binding

3 references

9 May 2019

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Mutation of an A-kinase-anchoring protein causes long-QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

potassium channel regulator activity

1 reference

24 April 2018

Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

protein binding

8 references

9 May 2019

CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

A Y2H-seq approach defines the human protein methyltransferase interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

molecular adaptor activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

6 references

24 April 2018

24 April 2018

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

9 May 2019

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

signaling receptor binding

1 reference

9 May 2019

Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

protein kinase A regulatory subunit binding

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

potassium channel regulator activity

molecular adaptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

4 references

1 January 2018

1 January 2018

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 January 2018

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

protein kinase A regulatory subunit binding

Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

molecular adaptor activity

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

8 April 2019

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

centrosome

Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

7 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

4 references

24 April 2018

24 April 2018

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

24 April 2018

intracellular membrane-bounded organelle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

voltage-gated potassium channel complex

1 reference

9 May 2019

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

cis-Golgi network

1 reference

24 April 2018

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

Golgi stack

1 reference

24 April 2018

Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

dendritic branch

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

synaptic membrane

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

soma

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

5 references

9 May 2019

9 May 2019

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

centrosome

Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

9 May 2019

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

extrinsic component of postsynaptic density membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

positive regulation of peptidyl-serine phosphorylation

biological process

1 reference

24 April 2018

Mutation of an A-kinase-anchoring protein causes long-QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

MAPK cascade

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

1 reference

24 April 2018

G2/M transition of mitotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

regulation of membrane repolarization

1 reference

9 May 2019

Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

regulation of heart rate by cardiac conduction

1 reference

9 May 2019

Mutation of an A-kinase-anchoring protein causes long-QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

positive regulation of potassium ion transmembrane transporter activity

1 reference

24 April 2018

Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

microtubule nucleation

1 reference

9 May 2019

Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

regulation of ventricular cardiac muscle cell membrane repolarization

1 reference

24 April 2018

Mutation of an A-kinase-anchoring protein causes long-QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

chemical synaptic transmission

1 reference

9 May 2019

Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

response to electrical stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

negative regulation of adenylate cyclase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

ciliary basal body-plasma membrane docking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

regulation of cardiac muscle cell action potential involved in regulation of contraction

1 reference

9 May 2019

Mutation of an A-kinase-anchoring protein causes long-QT syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

maintenance of centrosome location

1 reference

24 April 2018

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

regulation of G2/M transition of mitotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

regulation of Golgi organization

1 reference

24 April 2018

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99996&geneProductId=UniProtKB:Q99996

positive regulation of microtubule polymerization

1 reference

9 May 2019

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

positive regulation of potassium ion transmembrane transporter activity

cardiac conduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99996

1 reference

9 May 2019

physically interacts with

Viroporin 3a

Affinity Capture-MS

1 reference

https://thebiogrid.org/news/227

19 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

BioGRID

has part(s)

Pericentrin/AKAP-450 centrosomal targeting domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99996

ELK domain

1 reference

InterPro Release 71.0