Death associated protein kinase 2 (Q21173305)

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mammalian protein found in Homo sapiens

• death-associated protein kinase 2
• DRP-1
• DAP-kinase-related protein 1 beta isoform
• DAP-kinase-related protein 1
• DAP kinase 2
• DAPK2

edit

Language	Label	Description	Also known as
English	Death associated protein kinase 2	mammalian protein found in Homo sapiens	death-associated protein kinase 2 DRP-1 DAP-kinase-related protein 1 beta isoform DAP-kinase-related protein 1 DAP kinase 2 DAPK2

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UIK4

subclass of

protein

1 reference

stated in

UniProt

retrieved

1 December 2016

UniProt protein ID

Q9UIK4

part of

Protein kinase-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UIK4

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UIK4

encoded by

DAPK2

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UIK4

molecular function

transferase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

nucleotide binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

protein kinase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

calmodulin binding

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

kinase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

protein serine/threonine kinase activity

determination method or standard

TAS

IEA

2 references

retrieved

27 March 2018

stated in

The death-associated protein kinases: structure, function, and beyond

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

TAS

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

protein binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IPI

identical protein binding

determination method or standard

IPI

2 references

retrieved

8 April 2019

stated in

Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IPI

retrieved

8 April 2019

stated in

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IPI

ATP binding

determination method or standard

IDA

IEA

3 references

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

27 March 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

27 March 2018

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

protein serine/threonine kinase activity

determination method or standard

IBA

IEA

TAS

3 references

retrieved

8 April 2019

stated in

The death-associated protein kinases: structure, function, and beyond

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IBA

ATP binding

determination method or standard

IBA

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IBA

cell component

cytoplasm

determination method or standard

IDA

IEA

3 references

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

27 March 2018

stated in

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

retrieved

27 March 2018

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

autophagosome lumen

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

cytoplasmic vesicle

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

Golgi apparatus

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

intracellular membrane-bounded organelle

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

nucleus

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IBA

cytoplasm

determination method or standard

IBA

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

retrieved

8 April 2019

stated in

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IBA

biological process

regulation of apoptotic process

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

The death-associated protein kinases: structure, function, and beyond

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

TAS

intracellular signal transduction

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

regulation of intrinsic apoptotic signaling pathway

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IMP

phosphorylation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

protein phosphorylation

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

retrieved

8 April 2019

stated in

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IDA

positive regulation of eosinophil chemotaxis

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IMP

regulation of autophagy

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

The death-associated protein kinases: structure, function, and beyond

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

TAS

anoikis

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IMP

positive regulation of neutrophil chemotaxis

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IMP

protein autophosphorylation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

The death-associated protein kinases: structure, function, and beyond

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

TAS

neutrophil migration

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

apoptotic process

determination method or standard

TAS

IEA

2 references

retrieved

8 April 2019

stated in

Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UIK4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UIK4

determination method or standard

IEA

peptidyl-serine phosphorylation

determination method or standard

IBA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IBA

peptidyl-threonine phosphorylation

determination method or standard

IBA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UIK4&geneProductId=UniProtKB:Q9UIK4

determination method or standard

IBA

has part(s)

serine/threonine-protein kinase, active site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UIK4

protein kinase, ATP binding site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UIK4

protein kinase domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UIK4

Identifiers

RefSeq protein ID

NP_055141

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_011519715

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_011519716

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_011519717

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_011519719

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_011519723

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877532

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877533

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877534

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877535

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877536

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877537

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877538

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877539

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877540

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

XP_016877541

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

NP_001350659

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23604

UniProt protein ID

Q9UIK4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UIK4

Ensembl protein ID

ENSP00000261891

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000261891

ENSP00000408277

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000408277

ENSP00000453235

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000453235

ENSP00000484390

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000484390

ENSP00000452970

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000452970

ENSP00000453101

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000453101

ENSP00000453284

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000453284

ENSP00000453639

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000453639

PDB structure ID

1WMK

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

1WRZ

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

1Z9X

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

1ZUZ

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

1ZWS

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

2A27

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

2A2A

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

2CKE

1 reference

stated in

UniProt

UniProt protein ID

Q9UIK4

retrieved

21 March 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21173305&oldid=2023035947"