ASH2 like, histone lysine methyltransferase complex subunit (Q21130031)

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mammalian protein found in Homo sapiens
  • ash2 (absent, small, or homeotic)-like
  • ASH2-like protein
  • set1/Ash2 histone methyltransferase complex subunit ASH2
  • ASH2L
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Language Label Description Also known as
English
ASH2 like, histone lysine methyltransferase complex subunit
mammalian protein found in Homo sapiens
  • ash2 (absent, small, or homeotic)-like
  • ASH2-like protein
  • set1/Ash2 histone methyltransferase complex subunit ASH2
  • ASH2L

Statements

molecular function
protein binding
determination method or standard
IPI
24 references
retrieved
8 April 2019
stated in
Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks
GOA
curator
UniProt
UniProt protein ID
Q9UBL3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
GOA
curator
UniProt
UniProt protein ID
Q9UBL3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex
GOA
curator
UniProt
UniProt protein ID
Q9UBL3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes
GOA
curator
UniProt
UniProt protein ID
Q9UBL3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Molecular basis for DPY-30 association to COMPASS-like and NURF complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Structural and Biochemical Insights into MLL1 Core Complex Assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of the MLL2 complex as a coactivator for estrogen receptor alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
The mutational landscape of lethal castration-resistant prostate cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
retrieved
8 April 2019
stated in
Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UBL3
determination method or standard
IPI
cell component
biological process

Identifiers

 
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