Peroxisomal biogenesis factor 16 (Q21122505)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y5Y5

transporter of unknown biochemical mechanism

1 reference

Transporter Classification Database ID

9.A.17.1.2

hierarchical database ID heuristic

2 October 2019

based on heuristic

1 reference

13 November 2019

1 reference

13 November 2019

protein C-terminus binding

1 reference

8 April 2019

Analysis of human Pex19p's domain structure by pentapeptide scanning mutagenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

protein binding

7 references

8 April 2019

PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

The peroxisomal receptor Pex19p forms a helical mPTS recognition domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

1 reference

8 April 2019

peroxisomal membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

3 references

26 September 2017

Ensembl genome database project

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

26 September 2017

PEX14 is required for microtubule-based peroxisome motility in human cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

peroxisome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

4 references

8 April 2019

8 April 2019

Requirement for microtubules and dynein motors in the earliest stages of peroxisome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

3 references

26 September 2017

26 September 2017

Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

26 September 2017

Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

integral component of peroxisomal membrane

peroxisomal membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

4 references

8 April 2019

Ensembl genome database project

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

IBA

8 April 2019

PEX14 is required for microtubule-based peroxisome motility in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

HDA

endoplasmic reticulum

endoplasmic reticulum membrane

1 reference

8 April 2019

The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

protein targeting to peroxisome

biological process

1 reference

8 April 2019

Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

protein localization to endoplasmic reticulum

1 reference

26 September 2017

Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

peroxisome membrane biogenesis

peroxisome organization

Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

26 September 2017

Requirement for microtubules and dynein motors in the earliest stages of peroxisome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y5Y5&geneProductId=UniProtKB:Q9Y5Y5

26 September 2017

protein import into peroxisome matrix

1 reference

8 April 2019

Peroxisome synthesis in the absence of preexisting peroxisomes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

protein to membrane docking

1 reference

8 April 2019

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

ER-dependent peroxisome organization

1 reference

8 April 2019

The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

protein import into peroxisome membrane

1 reference

8 April 2019

The membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

peroxisome organization

Requirement for microtubules and dynein motors in the earliest stages of peroxisome biogenesis

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

ER-dependent peroxisome localization

IBA

1 reference

8 April 2019

Pex3p-dependent peroxisomal biogenesis initiates in the endoplasmic reticulum of human fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y5Y5

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9.A.17.1.2

2 references

Transporter Classification database

13 March 2020

Transporter Classification database