Spliceosome associated factor 3, U4/U6 recycling protein (Q21121239)

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mammalian protein found in Homo sapiens

Tip110
tat-interacting protein of 110 kDa
HIV-1 Tat-interacting protein of 110kDa
squamous cell carcinoma antigen recognized by T-cells 3
PRP24 homolog
squamous cell carcinoma antigen recognized by T cells 3
p110 nuclear RNA-binding protein
hSART-3
SART3
SART-3

Language	Label	Description	Also known as
English	Spliceosome associated factor 3, U4/U6 recycling protein	mammalian protein found in Homo sapiens	Tip110 tat-interacting protein of 110 kDa HIV-1 Tat-interacting protein of 110kDa squamous cell carcinoma antigen recognized by T-cells 3 PRP24 homolog squamous cell carcinoma antigen recognized by T cells 3 p110 nuclear RNA-binding protein hSART-3 SART3 SART-3

Statements

1 reference

13 November 2019

UniProt protein ID

Tetratricopeptide-like helical domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

RNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

LSM-interacting domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SART3, RNA recognition motif 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

SART3, RNA recognition motif 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA recognition motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

HAT (Half-A-TPR) repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

U6atac snRNA binding

determination method or standard

1 reference

8 April 2019

Recycling of the U12-type spliceosome requires p110, a component of the U6atac snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

histone binding

determination method or standard

1 reference

8 April 2019

The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

U4 snRNA binding

determination method or standard

3 references

8 April 2019

Human U4/U6 snRNP recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Recycling of the U12-type spliceosome requires p110, a component of the U6atac snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

protein binding

determination method or standard

5 references

8 April 2019

Human U4/U6 snRNP recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

nucleic acid binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

ubiquitin-specific protease binding

determination method or standard

U6 snRNA binding

determination method or standard

3 references

8 April 2019

Human U4/U6 snRNP recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Recycling of the U12-type spliceosome requires p110, a component of the U6atac snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

U4/U6 x U5 tri-snRNP complex

determination method or standard

1 reference

8 April 2019

p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

26 September 2017

Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

1 reference

8 April 2019

p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

1 reference

8 April 2019

Recycling of the U12-type spliceosome requires p110, a component of the U6atac snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

U4atac/U6atac snRNP

determination method or standard

1 reference

8 April 2019

Recycling of the U12-type spliceosome requires p110, a component of the U6atac snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

biological process

mRNA splicing, via spliceosome

determination method or standard

1 reference

26 September 2017

Human U4/U6 snRNP recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

nucleosome assembly

determination method or standard

1 reference

8 April 2019

The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

spliceosomal tri-snRNP complex assembly

determination method or standard

homeostasis of number of cells

determination method or standard

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

positive regulation of histone deubiquitination

determination method or standard

1 reference

8 April 2019

The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

hematopoietic stem cell proliferation

determination method or standard

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

mRNA processing

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

spliceosomal snRNP assembly

determination method or standard

cell morphogenesis

determination method or standard

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15020&geneProductId=UniProtKB:Q15020

determination method or standard

regulation of gene expression

determination method or standard

1 reference

8 April 2019

TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

regulation of alternative mRNA splicing, via spliceosome

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15020

determination method or standard

mRNA splicing, via spliceosome

determination method or standard

HAT (Half-A-TPR) repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

RNA recognition motif domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

LSM-interacting domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

SART3, RNA recognition motif 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

SART3, RNA recognition motif 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15020

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000228284

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000228284

ENSP00000414453

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000414453

ENSP00000448554

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000448554

ENSP00000449743

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000449743

ENSP00000446577

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000446577

ENSP00000447324

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000447324

ENSP00000447875

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000447875

ENSP00000449386

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000449386

ENSP00000449602

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000449602

ENSP00000498612

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000498612

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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