RISC-loading complex (Q21111251)

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A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the compl
  • miRLC
  • GO:0070578
  • microRNA loading complex
  • RISC loading complex
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English
RISC-loading complex
A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the compl
  • miRLC
  • GO:0070578
  • microRNA loading complex
  • RISC loading complex

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