Protein kinase AMP-activated non-catalytic subunit gamma 1 (Q21115161)

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mammalian protein found in Homo sapiens

• 5'-AMP-activated protein kinase, gamma-1 subunit
• PRKAG1
• 5'-AMP-activated protein kinase subunit gamma-1
• protein kinase, AMP-activated, gamma 1 non-catalytic subunit
• AMPK gamma1
• AMPK gamma-1 chain

edit

Language	Label	Description	Also known as
English	Protein kinase AMP-activated non-catalytic subunit gamma 1	mammalian protein found in Homo sapiens	5'-AMP-activated protein kinase, gamma-1 subunit PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit AMPK gamma1 AMPK gamma-1 chain

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P54619

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P54619

encoded by

PRKAG1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P54619

molecular function

nucleotide binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

protein kinase activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IDA

cAMP-dependent protein kinase activity

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

ADP binding

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

ISS

AMP-activated protein kinase activity

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

ISS

AMP binding

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

ISS

protein binding

determination method or standard

IPI

11 references

retrieved

8 April 2019

stated in

WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Identification and characterization of a novel folliculin-interacting protein FNIP2

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Network organization of the human autophagy system

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Toward an understanding of the protein interaction network of the human liver

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

retrieved

8 April 2019

stated in

Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IPI

cAMP-dependent protein kinase regulator activity

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

protein kinase binding

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IDA

ATP binding

determination method or standard

IEA

ISS

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

adenyl ribonucleotide binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

cell component

cytosol

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

membrane

determination method or standard

IDA

1 reference

retrieved

26 September 2017

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54619&geneProductId=UniProtKB:P54619

determination method or standard

IDA

nucleotide-activated protein kinase complex

determination method or standard

ISS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

ISS

extracellular exosome

determination method or standard

IDA

1 reference

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54619&geneProductId=UniProtKB:P54619

determination method or standard

IDA

nucleus

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

nucleoplasm

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

membrane

determination method or standard

HDA

1 reference

retrieved

8 April 2019

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

HDA

biological process

lipid metabolism

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

fatty acid metabolic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

regulation of glycolytic process

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

protein phosphorylation

determination method or standard

IDA

TAS

2 references

retrieved

8 April 2019

stated in

Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

retrieved

8 April 2019

stated in

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IDA

positive regulation of gene expression

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IDA

fatty acid biosynthetic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P54619

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

spermatogenesis

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposon

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

macroautophagy

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

signal transduction

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

positive regulation of protein kinase activity

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

regulation of signal transduction by p53 class mediator

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

regulation of macroautophagy

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

TAS

import into nucleus

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

regulation of protein serine/threonine kinase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54619

determination method or standard

IEA

Identifiers

RefSeq protein ID

NP_001193638

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

NP_001193639

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

NP_002724

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

XP_005269076

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

XP_005269077

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

XP_011536864

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

XP_016875111

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

XP_016875112

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5571

UniProt protein ID

P54619

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P54619

Ensembl protein ID

ENSP00000323867

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000323867

ENSP00000447433

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000447433

ENSP00000448972

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448972

ENSP00000446987

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000446987

ENSP00000447637

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000447637

ENSP00000447671

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000447671

ENSP00000448251

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448251

ENSP00000448290

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448290

ENSP00000448739

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448739

ENSP00000448873

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448873

ENSP00000449104

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449104

ENSP00000449121

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449121

ENSP00000449637

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449637

ENSP00000450112

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000450112

ENSP00000450273

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000450273

PDB structure ID

2UV4

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

2UV5

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

2UV6

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

2UV7

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

4CFE

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

4CFF

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

4RER

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

4REW

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

5EZV

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

4ZHX

1 reference

stated in

UniProt

UniProt protein ID

P54619

retrieved

1 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

edit

Wikiversity(0 entries)

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Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21115161&oldid=2022961151"