Cytoplasmic linker associated protein 1 (Q21114179)

CLIP-associating protein 1

1 reference

Armadillo-type fold

1 reference

TOG domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CLASP N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

HEAT, type 2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

microtubule binding

protein binding

6 references

8 April 2019

Microtubule-binding proteins CLASP1 and CLASP2 interact with actin filaments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

centrosome

3 references

8 April 2019

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

membrane

1 reference

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z460&geneProductId=UniProtKB:Q7Z460

cortical microtubule cytoskeleton

1 reference

8 April 2019

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

focal adhesion

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

centrosomal corona

1 reference

8 April 2019

Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

microtubule plus-end

1 reference

8 April 2019

A cryptic TOG domain with a distinct architecture underlies CLASP-dependent bipolar spindle formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

cell cortex

1 reference

8 April 2019

Role of CLASP2 in microtubule stabilization and the regulation of persistent motility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

spindle microtubule

1 reference

8 April 2019

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

basal cortex

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

extracellular exosome

1 reference

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z460&geneProductId=UniProtKB:Q7Z460

chromosome, centromeric region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

microtubule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

membrane

HDA

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

establishment of epithelial cell polarity

HDA

biological process

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

vesicle targeting

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

Golgi organization

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

mitotic spindle organization

1 reference

8 April 2019

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

regulation of epithelial to mesenchymal transition

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

regulation of microtubule cytoskeleton organization

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

positive regulation of epithelial cell migration

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

exit from mitosis

1 reference

8 April 2019

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

establishment or maintenance of cell polarity

NAS

1 reference

8 April 2019

CLIPs and CLASPs and cellular dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

positive regulation of extracellular matrix disassembly

NAS

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

positive regulation of basement membrane assembly involved in embryonic body morphogenesis

negative regulation of microtubule depolymerization

mitotic spindle assembly

1 reference

8 April 2019

A cryptic TOG domain with a distinct architecture underlies CLASP-dependent bipolar spindle formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

microtubule anchoring

G2/M transition of mitotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

microtubule bundle formation

1 reference

8 April 2019

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

negative regulation of microtubule polymerization or depolymerization

1 reference

8 April 2019

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

positive regulation of microtubule polymerization

1 reference

8 April 2019

A cryptic TOG domain with a distinct architecture underlies CLASP-dependent bipolar spindle formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

regulation of focal adhesion assembly

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

negative regulation of wound healing, spreading of epidermal cells

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

positive regulation of exocytosis

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

negative regulation of stress fiber assembly

1 reference

8 April 2019

CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

establishment of spindle orientation

MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

8 April 2019

MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

astral microtubule organization

1 reference

8 April 2019

RanGTP and CLASP1 cooperate to position the mitotic spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

microtubule organizing center organization

1 reference

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

establishment of mitotic spindle localization

1 reference

8 April 2019

RanGTP and CLASP1 cooperate to position the mitotic spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

regulation of gastrulation

1 reference

8 April 2019

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

microtubule cytoskeleton organization

microtubule nucleation

1 reference

8 April 2019

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

sister chromatid cohesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7Z460&geneProductId=UniProtKB:Q7Z460

1 reference

26 September 2017

ciliary basal body-plasma membrane docking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

regulation of G2/M transition of mitotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7Z460

1 reference

8 April 2019

has part(s)

CLASP N-terminal domain

1 reference

HEAT, type 2

1 reference

TOG domain

1 reference