Polycomb group ring finger 2 (Q21102176)

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mammalian protein found in Homo sapiens

• PCGF2
• polycomb group RING finger protein 2
• zinc finger protein 144
• DNA-binding protein Mel-18
• ring finger protein 110

edit

Language	Label	Description	Also known as
English	Polycomb group ring finger 2	mammalian protein found in Homo sapiens	PCGF2 polycomb group RING finger protein 2 zinc finger protein 144 DNA-binding protein Mel-18 ring finger protein 110

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35227

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35227

encoded by

PCGF2

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35227

molecular function

metal ion binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

chromatin binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

DNA-binding transcription factor activity

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

TAS

DNA binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

protein binding

determination method or standard

IPI

8 references

retrieved

8 April 2019

stated in

Structure of the Polycomb Group Protein PCGF1 in Complex with BCOR Reveals Basis for Binding Selectivity of PCGF Homologs

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

retrieved

8 April 2019

stated in

A High-Density Map for Navigating the Human Polycomb Complexome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

retrieved

8 April 2019

stated in

Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

retrieved

8 April 2019

stated in

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

retrieved

8 April 2019

stated in

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

retrieved

8 April 2019

stated in

Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

retrieved

8 April 2019

stated in

Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IPI

promoter-specific chromatin binding

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IBA

cell component

nucleoplasm

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

TAS

nucleus

determination method or standard

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

retrieved

8 April 2019

stated in

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IDA

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IDA

sex chromatin

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

nuclear body

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

PcG protein complex

determination method or standard

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

retrieved

8 April 2019

stated in

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IDA

retrieved

8 April 2019

stated in

BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IDA

PRC1 complex

determination method or standard

IDA

1 reference

retrieved

27 February 2018

stated in

Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35227&geneProductId=UniProtKB:P35227

determination method or standard

IDA

PRC1 complex

determination method or standard

IBA

IDA

2 references

retrieved

8 April 2019

stated in

Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IBA

biological process

anterior/posterior pattern specification

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35227&geneProductId=UniProtKB:P35227

determination method or standard

IEA

negative regulation of apoptotic signaling pathway

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

embryonic skeletal system morphogenesis

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

cellular response to hydrogen peroxide

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

histone acetylation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

in utero embryonic development

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35227&geneProductId=UniProtKB:P35227

determination method or standard

IEA

embryonic skeletal system development

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

negative regulation of transcription by RNA polymerase II

determination method or standard

IEA

IMP

2 references

retrieved

27 February 2018

stated in

Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35227&geneProductId=UniProtKB:P35227

determination method or standard

IMP

retrieved

27 February 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35227&geneProductId=UniProtKB:P35227

determination method or standard

IEA

histone H2A-K119 monoubiquitination

determination method or standard

IMP

1 reference

retrieved

27 February 2018

stated in

BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35227&geneProductId=UniProtKB:P35227

determination method or standard

IMP

negative regulation of G0 to G1 transition

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

TAS

negative regulation of transcription by RNA polymerase II

determination method or standard

IBA

IEA

IMP

3 references

retrieved

8 April 2019

stated in

Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IBA

histone H2A-K119 monoubiquitination

determination method or standard

IBA

IMP

2 references

retrieved

8 April 2019

stated in

BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase

GOA

curator

UniProt

UniProt protein ID

P35227

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IMP

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35227

determination method or standard

IBA

Identifiers

RefSeq protein ID

NP_009075

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7703

XP_005257697

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7703

XP_016880505

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7703

NP_001356543

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7703

NP_001356544

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

7703

UniProt protein ID

P35227

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P35227

Ensembl protein ID

ENSP00000478517

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000478517

ENSP00000478970

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000478970

ENSP00000482063

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000482063

ENSP00000482815

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000482815

ENSP00000488868

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000488868

ENSP00000488872

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000488872

ENSP00000487914

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000487914

ENSP00000481656

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000481656

ENSP00000484201

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000484201

ENSP00000487834

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000487834

ENSP00000484721

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000484721

ENSP00000483741

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000483741

ENSP00000487887

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000487887

ENSP00000487929

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000487929

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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