INO80 complex ATPase subunit (Q21108221)

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mammalian protein found in Homo sapiens

DNA helicase INO80
putative DNA helicase INO80 complex homolog 1
INO80 homolog
INO80
DNA helicase-related protein INO80
DNA helicase-related INO80 complex homolog 1
chromatin-remodeling ATPase INO80
INO80 complex subunit A
homolog of yeast INO80

Language	Label	Description	Also known as
English	INO80 complex ATPase subunit	mammalian protein found in Homo sapiens	DNA helicase INO80 putative DNA helicase INO80 complex homolog 1 INO80 homolog INO80 DNA helicase-related protein INO80 DNA helicase-related INO80 complex homolog 1 chromatin-remodeling ATPase INO80 INO80 complex subunit A homolog of yeast INO80

Statements

1 reference

13 November 2019

UniProt protein ID

DNA helicase Ino80

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ULG1

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ULG1

SNF2-like, N-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ULG1

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SNF2-related, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DBINO domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

Characterization of a human SWI2/SNF2 like protein hINO80: demonstration of catalytic and DNA binding activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

helicase activity

determination method or standard

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ULG1&geneProductId=UniProtKB:Q9ULG1

determination method or standard

alpha-tubulin binding

determination method or standard

1 reference

8 April 2019

Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

protein binding

determination method or standard

6 references

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

A High-Density Map for Navigating the Human Polycomb Complexome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

Structure and regulation of the human INO80-nucleosome complex.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

The human actin-related protein hArp5: nucleo-cytoplasmic shuttling and involvement in DNA repair

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

hydrolase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

ATP-dependent activity, acting on DNA

determination method or standard

1 reference

8 April 2019

Characterization of a human SWI2/SNF2 like protein hINO80: demonstration of catalytic and DNA binding activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

ATPase activity

determination method or standard

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ULG1&geneProductId=UniProtKB:Q9ULG1

determination method or standard

histone binding

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

3'-5' DNA helicase activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ULG1&geneProductId=UniProtKB:Q9ULG1

determination method or standard

21 June 2018

Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ULG1&geneProductId=UniProtKB:Q9ULG1

determination method or standard

21 June 2018

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ULG1&geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

Characterization of a human SWI2/SNF2 like protein hINO80: demonstration of catalytic and DNA binding activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

plasma membrane

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

intermediate filament cytoskeleton

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

biological process

DNA recombination

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

cellular response to UV

determination method or standard

1 reference

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

positive regulation of nuclear cell cycle DNA replication

determination method or standard

1 reference

8 April 2019

Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

cellular response to DNA damage stimulus

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

spindle assembly

determination method or standard

1 reference

8 April 2019

Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

regulation of G1/S transition of mitotic cell cycle

determination method or standard

1 reference

8 April 2019

Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

positive regulation of cell growth

determination method or standard

1 reference

8 April 2019

Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

double-strand break repair

determination method or standard

1 reference

8 April 2019

Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

double-strand break repair via homologous recombination

determination method or standard

1 reference

8 April 2019

A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

mitotic sister chromatid segregation

determination method or standard

1 reference

8 April 2019

Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

cellular response to ionizing radiation

determination method or standard

1 reference

8 April 2019

Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

UV-damage excision repair

determination method or standard

1 reference

8 April 2019

INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

protein deubiquitination

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

chromatin remodeling

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

DNA duplex unwinding

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

regulation of transcription from RNA polymerase II promoter in response to stress

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULG1

determination method or standard

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000384686

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384686

ENSP00000452806

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000452806

ENSP00000453677

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000453677

ENSP00000454057

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454057

ENSP00000483661

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000483661

ENSP00000497609

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000497609

Sitelinks

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