Hydrogen voltage gated channel 1 (Q21107673)

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mammalian protein found in Homo sapiens

• HV1
• voltage-gated hydrogen channel 1
• HVCN1
• Hydrogen voltage-gated channel 1
• voltage sensor domain-only protein

edit

Language	Label	Description	Also known as
English	Hydrogen voltage gated channel 1	mammalian protein found in Homo sapiens	HV1 voltage-gated hydrogen channel 1 HVCN1 Hydrogen voltage-gated channel 1 voltage sensor domain-only protein

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96D96

subclass of

Voltage-gated Proton Channel

0 references

part of

Voltage-gated hydrogen channel 1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96D96

Voltage-dependent channel domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96D96

Voltage-gated Proton Channel

1 reference

Transporter Classification Database ID

1.A.51.1.2

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

Ion transport domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Voltage-gated hydrogen channel 1, C-terminal membrane-localisation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96D96

encoded by

HVCN1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96D96

molecular function

ion channel activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

voltage-gated cation channel activity

determination method or standard

TAS

1 reference

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96D96&geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

voltage-gated ion channel activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

voltage-gated proton channel activity

determination method or standard

IDA

ISS

IEA

5 references

retrieved

8 April 2019

stated in

A voltage sensor-domain protein is a voltage-gated proton channel

GOA

curator

HUGO Gene Nomenclature Committee

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

retrieved

8 April 2019

stated in

A voltage-gated proton-selective channel lacking the pore domain

GOA

curator

HUGO Gene Nomenclature Committee

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

identical protein binding

determination method or standard

IEA

IPI

2 references

retrieved

8 April 2019

stated in

Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IPI

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

voltage-gated cation channel activity

determination method or standard

EXP

2 references

retrieved

8 April 2019

stated in

Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

EXP

retrieved

8 April 2019

stated in

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

EXP

cell component

membrane

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

integral component of membrane

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

A voltage-gated proton-selective channel lacking the pore domain

GOA

curator

HUGO Gene Nomenclature Committee

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

plasma membrane

determination method or standard

TAS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

secretory granule membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

specific granule membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

integral component of plasma membrane

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

phagocytic vesicle membrane

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

biological process

transmembrane transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

regulation of ion transmembrane transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

cellular response to pH

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

response to zinc ion

determination method or standard

IDA

ISS

IEA

3 references

retrieved

8 April 2019

stated in

A voltage sensor-domain protein is a voltage-gated proton channel

GOA

curator

HUGO Gene Nomenclature Committee

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

A voltage-gated proton-selective channel lacking the pore domain

GOA

curator

HUGO Gene Nomenclature Committee

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

ion transport

determination method or standard

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

cellular response to zinc ion

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

sperm-egg recognition

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

response to pH

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

A voltage sensor-domain protein is a voltage-gated proton channel

GOA

curator

HUGO Gene Nomenclature Committee

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

neutrophil degranulation

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

proton transmembrane transport

determination method or standard

IDA

IEA

ISS

4 references

retrieved

8 April 2019

stated in

A voltage sensor-domain protein is a voltage-gated proton channel

GOA

curator

HUGO Gene Nomenclature Committee

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IEA

retrieved

8 April 2019

stated in

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

GOA

curator

UniProt

UniProt protein ID

Q96D96

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

IDA

cell redox homeostasis

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96D96

determination method or standard

TAS

exact match

https://identifiers.org/uniprot:Q96D96

1 reference

stated in

Identifiers.org

UniProt protein ID

Q96D96

reference URL

https://registry.identifiers.org/registry/uniprot

http://purl.uniprot.org/uniprot/Q96D96

1 reference

stated in

Identifiers.org

UniProt protein ID

Q96D96

reference URL

https://registry.identifiers.org/registry/uniprot

https://www.ncbi.nlm.nih.gov/protein/Q96D96

1 reference

stated in

Identifiers.org

UniProt protein ID

Q96D96

reference URL

https://registry.identifiers.org/registry/uniprot

has part(s)

Ion transport domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96D96

Voltage-gated hydrogen channel 1, C-terminal membrane-localisation domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96D96

Identifiers

RefSeq protein ID

NP_001035196

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

NP_001243342

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

NP_115745

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_005254005

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537140

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537141

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537142

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537143

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537144

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537146

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537147

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537148

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_011537149

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_016875515

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_016875516

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

XP_024304993

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84329

UniProt protein ID

Q96D96

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96D96

Ensembl protein ID

ENSP00000242607

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000242607

ENSP00000349181

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000349181

ENSP00000412052

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000412052

ENSP00000449601

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000449601

ENSP00000479812

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000479812

ENSP00000447227

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000447227

ENSP00000448379

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000448379

ENSP00000450106

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000450106

PDB structure ID

3A2A

1 reference

stated in

UniProt

UniProt protein ID

Q96D96

retrieved

9 August 2016

language of work or name

English

Transporter Classification Database ID

1.A.51.1.2

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

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Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21107673&oldid=2022930882"