Mitochondrial elongation factor 1 (Q21105388)

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mammalian protein found in Homo sapiens

• MIEF1 microprotein
• SMCR7-like protein
• mitochondrial dynamics protein of 51 kDa
• Smith-Magenis syndrome chromosome region, candidate 7-like
• MIEF1
• mitochondrial dynamic protein MID51
• mitochondrial dynamics protein MID51
• mitochondrial dynamic protein of 51 kDa
• smith-Magenis syndrome chromosomal region candidate gene 7 protein-like
• alternative MIEF1 protein

edit

Language	Label	Description	Also known as
English	Mitochondrial elongation factor 1	mammalian protein found in Homo sapiens	MIEF1 microprotein SMCR7-like protein mitochondrial dynamics protein of 51 kDa Smith-Magenis syndrome chromosome region, candidate 7-like MIEF1 mitochondrial dynamic protein MID51 mitochondrial dynamics protein MID51 mitochondrial dynamic protein of 51 kDa smith-Magenis syndrome chromosomal region candidate gene 7 protein-like alternative MIEF1 protein

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

22 April 2020

UniProt protein ID

L0R8F8

part of

Mab-21 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

22 April 2020

UniProt protein ID

L0R8F8

encoded by

MIEF1

1 reference

stated in

UniProt

retrieved

22 April 2020

UniProt protein ID

L0R8F8

molecular function

nucleotide binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IEA

ADP binding

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

protein binding

determination method or standard

IPI

5 references

retrieved

8 April 2019

stated in

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

8 April 2019

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

8 April 2019

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

8 April 2019

stated in

Towards a proteome-scale map of the human protein–protein interaction network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

GDP binding

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

identical protein binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

protein binding

determination method or standard

IBA

IPI

6 references

retrieved

7 November 2018

stated in

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

7 November 2018

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

7 November 2018

stated in

Towards a proteome-scale map of the human protein–protein interaction network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

7 November 2018

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

7 November 2018

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

7 November 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IBA

identical protein binding

determination method or standard

IBA

IPI

2 references

retrieved

7 November 2018

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IPI

retrieved

7 November 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IBA

cell component

integral component of membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IEA

mitochondrial outer membrane

determination method or standard

IDA

IEA

3 references

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IEA

retrieved

27 March 2018

stated in

MiD49 and MiD51, new components of the mitochondrial fission machinery

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

27 March 2018

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

peroxisome

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

TAS

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IEA

mitochondrion

determination method or standard

IDA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IEA

retrieved

9 May 2019

stated in

Structures of the human mitochondrial ribosome in native states of assembly.

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IDA

mitochondrion

determination method or standard

IBA

IDA

IEA

5 references

retrieved

7 November 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IEA

retrieved

7 November 2018

stated in

Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

7 November 2018

stated in

Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

7 November 2018

stated in

GOA

curator

LifeDB

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

7 November 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IBA

mitochondrial outer membrane

determination method or standard

IBA

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IEA

retrieved

8 April 2019

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

8 April 2019

stated in

MiD49 and MiD51, new components of the mitochondrial fission machinery

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IBA

mitochondrial matrix

determination method or standard

IDA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IEA

retrieved

9 May 2019

stated in

MIEF1 Microprotein Regulates Mitochondrial Translation

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IDA

mitochondrial large ribosomal subunit

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

Structures of the human mitochondrial ribosome in native states of assembly.

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IDA

biological process

mitochondrial fusion

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IMP

positive regulation of mitochondrial fission

determination method or standard

IDA

TAS

3 references

retrieved

27 March 2018

stated in

Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

TAS

retrieved

27 March 2018

stated in

Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

27 March 2018

stated in

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NQG6&geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

mitochondrial fission

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IMP

positive regulation of protein targeting to membrane

determination method or standard

IDA

2 references

retrieved

8 April 2019

stated in

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

8 April 2019

stated in

Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

positive regulation of mitochondrial fission

determination method or standard

IBA

IDA

TAS

4 references

retrieved

8 April 2019

stated in

Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

TAS

retrieved

8 April 2019

stated in

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

8 April 2019

stated in

Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

GOA

curator

UniProt

UniProt protein ID

Q9NQG6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NQG6

determination method or standard

IBA

regulation of translation

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IEA

ribosome biogenesis

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IEA

positive regulation of mitochondrial translation

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

MIEF1 Microprotein Regulates Mitochondrial Translation

GOA

curator

UniProt

UniProt protein ID

L0R8F8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:L0R8F8

determination method or standard

IDA

has part(s)

Mab-21 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9NQG6

Identifiers

RefSeq protein ID

NP_001291493

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

54471

NP_061881

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

54471

XP_011528538

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

54471

XP_011528539

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

54471

XP_011528540

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

54471

XP_016884327

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

54471

UniProt protein ID

L0R8F8

1 reference

stated in

UniProt

retrieved

22 April 2020

UniProt protein ID

L0R8F8

Ensembl protein ID

ENSP00000327124

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000327124

ENSP00000404096

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000404096

ENSP00000385191

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000385191

ENSP00000390029

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000390029

ENSP00000385110

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000385110

ENSP00000413730

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000413730

PDB structure ID

4NXT

1 reference

stated in

UniProt

UniProt protein ID

Q9NQG6

retrieved

20 March 2016

language of work or name

English

4NXU

1 reference

stated in

UniProt

UniProt protein ID

Q9NQG6

retrieved

20 March 2016

language of work or name

English

4NXV

1 reference

stated in

UniProt

UniProt protein ID

Q9NQG6

retrieved

20 March 2016

language of work or name

English

4NXW

1 reference

stated in

UniProt

UniProt protein ID

Q9NQG6

retrieved

20 March 2016

language of work or name

English

4NXX

1 reference

stated in

UniProt

UniProt protein ID

Q9NQG6

retrieved

20 March 2016

language of work or name

English

 

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21105388&oldid=2022924397"