Dimethylglycine dehydrogenase (Q21104652)

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mammalian protein found in Homo sapiens

• ME2GLYDH
• DMGDH
• dimethylglycine dehydrogenase, mitochondrial

edit

Language	Label	Description	Also known as
English	Dimethylglycine dehydrogenase	mammalian protein found in Homo sapiens	ME2GLYDH DMGDH dimethylglycine dehydrogenase, mitochondrial

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UI17

part of

FAD/NAD(P)-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI17

Glycine cleavage T-protein/YgfZ, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI17

GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI17

Aminomethyltransferase, folate-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FAD dependent oxidoreductase, central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glycine cleavage T-protein, C-terminal barrel domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FAD dependent oxidoreductase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UI17

encoded by

DMGDH

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UI17

molecular function

electron transfer activity

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

Structure and analysis of the human dimethylglycine dehydrogenase gene

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

NAS

oxidoreductase activity

determination method or standard

IEA

2 references

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

31 October 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

dimethylglycine dehydrogenase activity

determination method or standard

IEA

IMP

TAS

3 references

retrieved

31 October 2017

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

TAS

retrieved

31 October 2017

stated in

Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IMP

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

RNA binding

determination method or standard

IDA

1 reference

retrieved

31 October 2017

stated in

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IDA

RNA binding

determination method or standard

HDA

1 reference

retrieved

8 April 2019

stated in

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

HDA

oxidoreductase activity

determination method or standard

IBA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IBA

dimethylglycine dehydrogenase activity

determination method or standard

IBA

IEA

IMP

TAS

4 references

retrieved

1 January 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

TAS

retrieved

1 January 2018

stated in

Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IMP

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IBA

dimethylglycine dehydrogenase activity

determination method or standard

IBA

IEA

IMP

3 references

retrieved

8 April 2019

stated in

Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IBA

cell component

mitochondrion

determination method or standard

IDA

IEA

3 references

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

31 October 2017

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

31 October 2017

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UI17&geneProductId=UniProtKB:Q9UI17

determination method or standard

IDA

mitochondrial matrix

determination method or standard

IBA

NAS

TAS

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

TAS

retrieved

8 April 2019

stated in

Structure and analysis of the human dimethylglycine dehydrogenase gene

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

NAS

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IBA

cytoplasm

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IBA

mitochondrion

determination method or standard

IBA

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IBA

biological process

amino-acid betaine catabolic process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

choline metabolic process

determination method or standard

NAS

1 reference

retrieved

8 April 2019

stated in

Structure and analysis of the human dimethylglycine dehydrogenase gene

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

NAS

choline catabolic process

determination method or standard

IMP

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

TAS

retrieved

8 April 2019

stated in

Defect in dimethylglycine dehydrogenase, a new inborn error of metabolism: NMR spectroscopy study

GOA

curator

UniProt

UniProt protein ID

Q9UI17

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IMP

electron transport chain

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UI17

determination method or standard

IEA

exact match

https://identifiers.org/uniprot:Q9UI17

1 reference

stated in

Identifiers.org

UniProt protein ID

Q9UI17

reference URL

https://registry.identifiers.org/registry/uniprot

http://purl.uniprot.org/uniprot/Q9UI17

1 reference

stated in

Identifiers.org

UniProt protein ID

Q9UI17

reference URL

https://registry.identifiers.org/registry/uniprot

https://www.ncbi.nlm.nih.gov/protein/Q9UI17

1 reference

stated in

Identifiers.org

UniProt protein ID

Q9UI17

reference URL

https://registry.identifiers.org/registry/uniprot

has part(s)

Aminomethyltransferase, folate-binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI17

Glycine cleavage T-protein, C-terminal barrel domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI17

FAD dependent oxidoreductase, central domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI17

FAD dependent oxidoreductase domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UI17

Identifiers

RefSeq protein ID

NP_037523

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

29958

XP_006714660

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

29958

XP_011541657

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

29958

UniProt protein ID

Q9UI17

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UI17

Ensembl protein ID

ENSP00000255189

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000255189

ENSP00000427834

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000427834

ENSP00000428092

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000428092

ENSP00000428995

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000428995

ENSP00000430133

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000430133

ENSP00000430972

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000430972

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21104652&oldid=2022922249"