New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis (Q21091034)

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scientific article published in 2011

Language	Label	Description	Also known as
English	New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis	scientific article published in 2011

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scholarly article

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New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis (English)

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high-throughput screening

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Mycobacterium tuberculosis

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1 reference

based on heuristic

inferred from title

2

object named as

Ulrich Strych

author given names

Ulrich

author last names

Strych

1 reference

PubMed publication ID

15 August 2022

author name string

Karen G Anthony

1

author given names

Karen G

author last names

Anthony

1 reference

PubMed publication ID

15 August 2022

Kacheong R Yeung

3

author given names

Kacheong R

author last names

Yeung

1 reference

PubMed publication ID

15 August 2022

Carolyn S Shoen

4

author given names

Carolyn S

author last names

Shoen

1 reference

PubMed publication ID

15 August 2022

Oriana Perez

5

author given names

Oriana

author last names

Perez

1 reference

PubMed publication ID

15 August 2022

Kurt L Krause

6

author given names

Kurt L

author last names

Krause

1 reference

PubMed publication ID

15 August 2022

Michael H Cynamon

7

author given names

Michael H

author last names

Cynamon

1 reference

PubMed publication ID

15 August 2022

Paul A Aristoff

8

author given names

Paul A

author last names

Aristoff

1 reference

PubMed publication ID

15 August 2022

Raymond A Koski

9

author given names

Raymond A

author last names

Koski

1 reference

PubMed publication ID

15 August 2022

language of work or name

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publication date

2011

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6

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5

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e20374

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copyright license

Creative Commons Attribution 4.0 International

26 May 2011

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April 2022 Public Data File from Crossref

copyright status

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Mechanism of d -Cycloserine Action: Alanine Racemase from Escherichia coli W

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

19 March 2017

A Side Reaction of Alanine Racemase: Transamination of Cycloserine,

1 reference

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19 March 2017

Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

19 March 2017

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

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19 March 2017

The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site

1 reference

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19 March 2017

Genes required for mycobacterial growth defined by high density mutagenesis

1 reference

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19 March 2017

Characterization of the alanine racemases from two mycobacteria

1 reference

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19 March 2017

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 reference

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19 March 2017

The growing burden of tuberculosis: global trends and interactions with the HIV epidemic

1 reference

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7 April 2017

Drugs in development for tuberculosis

1 reference

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12 September 2017

Extensively drug-resistant tuberculosis: "there must be some kind of way out of here".

1 reference

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12 September 2017

Tuberculosis drug development: progress, challenges, and the road ahead

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

12 September 2017

The alanine racemase of Mycobacterium smegmatis is essential for growth in the absence of D-alanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

12 September 2017

Key issues in multidrug-resistant tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

12 September 2017

New tuberculosis drugs in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

12 September 2017

Challenges in tuberculosis drug research and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

12 September 2017

Reaction specificity in pyridoxal phosphate enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

12 September 2017

Enzymes in the D-alanine branch of bacterial cell wall peptidoglycan assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

12 September 2017

Multidrug-resistant tuberculosis in Denmark 1993-1995

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

27 September 2017

Inhibition of cell wall biosynthesis by analogues and alanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

27 September 2017

In vitro antituberculosis activities of ACH-702, a novel isothiazoloquinolone, against quinolone-susceptible and quinolone-resistant isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

30 May 2018

Barriers to reaching the targets for tuberculosis control: multidrug-resistant tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

30 May 2018

Adverse neurological reactions in patients with multidrug-resistant pulmonary tuberculosis after coadministration of cycloserine and ofloxacin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

30 May 2018

Inactivation of the dadB Salmonella typhimurium alanine racemase by D and L isomers of beta-substituted alanines: kinetics, stoichiometry, active site peptide sequencing, and reaction mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

30 May 2018

1-Aminocyclopropanephosphonate: time-dependent inactivation of 1-aminocyclopropanecarboxylate deaminase and Bacillus stearothermophilus alanine racemase by slow dissociation behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

30 May 2018

Biosynthetic alanine racemase of Salmonella typhimurium: purification and characterization of the enzyme encoded by the alr gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

30 May 2018

Inhibition of alanine racemase by alanine phosphonate: detection of an imine linkage to pyridoxal 5'-phosphate in the enzyme-inhibitor complex by solid-state 15N nuclear magnetic resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102704

30 May 2018

Molecular dynamics studies of alanine racemase: a structural model for drug design.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020374

21 January 2018

A model for enzyme-substrate interaction in alanine racemase

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020374

21 January 2018

A structure-based design approach for the identification of novel inhibitors: application to an alanine racemase.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020374

21 January 2018

N(2)-substituted D,L-cycloserine derivatives: synthesis and evaluation as alanine racemase inhibitors

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020374

21 January 2018

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29 November 2018

Identifiers

10.1371/JOURNAL.PONE.0020374

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2011PLoSO...620374A

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release_6xfsv5qeprc2jfeueink6mtazq

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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