E2F transcription factor 2 Dmel_CG1071 (Q29812234)

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Protein found in Drosophila melanogaster

• CG1071 gene product from transcript CG1071-RB
• CG1071-PA
• E2f2-PA
• CG1071-PB
• E2f2
• E2f2-PB
• E2F transcription factor 2

edit

Language	Label	Description	Also known as
English	E2F transcription factor 2 Dmel_CG1071	Protein found in Drosophila melanogaster	CG1071 gene product from transcript CG1071-RB CG1071-PA E2f2-PA CG1071-PB E2f2 E2f2-PB E2F transcription factor 2

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O77051

part of

winged helix DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O77051

Winged helix-like DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O77051

E2F family

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O77051

E2F-DP heterodimerization region

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O77051

E2F/DP family, winged-helix DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O77051

encoded by

E2f2

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O77051

molecular function

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

IPI

2 references

retrieved

31 January 2018

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IPI

retrieved

8 April 2019

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IPI

DNA binding

determination method or standard

IEA

1 reference

retrieved

7 November 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IEA

DNA-binding transcription factor activity

determination method or standard

IEA

1 reference

retrieved

7 November 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IEA

protein binding

determination method or standard

IPI

4 references

retrieved

8 April 2019

stated in

Functional antagonism between E2F family members

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IPI

retrieved

8 April 2019

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IPI

retrieved

8 April 2019

stated in

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IPI

retrieved

8 April 2019

stated in

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IPI

transcription factor binding

determination method or standard

IPI

1 reference

retrieved

31 January 2018

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IPI

protein heterodimerization activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Functional antagonism between E2F family members

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method or standard

IBA

2 references

retrieved

10 September 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IBA

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IBA

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

IBA

IPI

4 references

retrieved

10 September 2018

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IPI

retrieved

10 September 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IBA

retrieved

1 January 2018

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IPI

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IBA

transcription factor binding

determination method or standard

IBA

IPI

2 references

retrieved

8 April 2019

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IPI

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

sequence-specific DNA binding

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

DNA binding

determination method or standard

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

DNA-binding transcription factor activity

determination method or standard

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

cell component

chromatin

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

nucleus

determination method or standard

IEA

1 reference

retrieved

7 November 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IEA

transcription regulator complex

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IEA

Myb complex

determination method or standard

IDA

2 references

retrieved

8 April 2019

stated in

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

retrieved

8 April 2019

stated in

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

Rb-E2F complex

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

RNA polymerase II transcription regulator complex

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

nucleus

determination method or standard

HDA

IBA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

retrieved

8 April 2019

stated in

A genome-wide resource for the analysis of protein localisation in Drosophila

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

HDA

biological process

negative regulation of transcription by RNA polymerase II

determination method or standard

IMP

2 references

retrieved

31 January 2018

stated in

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IMP

retrieved

31 January 2018

stated in

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IMP

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

31 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O77051&geneProductId=UniProtKB:O77051

determination method or standard

IEA

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IEA

endomitotic cell cycle

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

TAS

imaginal disc development

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

TAS

negative regulation of DNA replication

determination method or standard

IMP

2 references

retrieved

8 April 2019

stated in

Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IMP

retrieved

8 April 2019

stated in

Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IMP

DNA endoreduplication

determination method or standard

IGI

IMP

2 references

retrieved

8 April 2019

stated in

Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IMP

retrieved

8 April 2019

stated in

Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IGI

negative regulation of apoptotic process

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

negative regulation of transcription, DNA-templated

determination method or standard

IDA

TAS

3 references

retrieved

8 April 2019

stated in

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

TAS

retrieved

8 April 2019

stated in

p55, the Drosophila ortholog of RbAp46/RbAp48, is required for the repression of dE2F2/RBF-regulated genes

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

retrieved

8 April 2019

stated in

dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster

GOA

curator

UniProt

UniProt protein ID

O77051

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

oogenesis

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

TAS

negative regulation of G1/S transition of mitotic cell cycle

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IDA

G1/S transition of mitotic cell cycle

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

TAS

negative regulation of transcription by RNA polymerase II

determination method or standard

IBA

IMP

3 references

retrieved

8 April 2019

stated in

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IMP

retrieved

8 April 2019

stated in

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IMP

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

positive regulation of transcription by RNA polymerase II

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

regulation of cell cycle

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IBA

positive regulation of transcription regulatory region DNA binding

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

An alternatively spliced form affecting the Marked Box domain of Drosophila E2F1 is required for proper cell cycle regulation

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O77051

determination method or standard

IMP

has part(s)

E2F/DP family, winged-helix DNA-binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O77051

Identifiers

RefSeq protein ID

NP_001286115

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

35381

NP_477355

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

35381

UniProt protein ID

O77051

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

O77051

Ensembl protein ID

FBpp0312101

1 reference

stated in

ensembl Release 106

Ensembl protein ID

FBpp0312101

FBpp0081029

1 reference

stated in

ensembl Release 106

Ensembl protein ID

FBpp0081029

 

Sitelinks

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q29812234&oldid=2030265975"