Smaug Dmel_CG5263 (Q29818405)

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Protein found in Drosophila melanogaster

smg-PB
CG5263-PD
CG5263-PE
smg-PE
dSmaug
CG5263-PC
smau
smg-PA
smaug
smg-PD
smg-PC
CG5263 gene product from transcript CG5263-RB
CG5263-PA
smg
CG5263-PB

Language	Label	Description	Also known as
English	Smaug Dmel_CG5263	Protein found in Drosophila melanogaster	smg-PB CG5263-PD CG5263-PE smg-PE dSmaug CG5263-PC smau smg-PA smaug smg-PD smg-PC CG5263 gene product from transcript CG5263-RB CG5263-PA smg CG5263-PB

Statements

1 reference

25 May 2022

UniProt protein ID

Smaug, PHAT domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23972

Armadillo-type fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23972

Sterile alpha motif/pointed domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23972

Protein Smaug, SAM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Smaug, PHAT analogous topology, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sterile alpha motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

translation repressor activity, mRNA regulatory element binding

determination method or standard

1 reference

8 April 2019

Translational repressors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

determination method or standard

1 reference

31 January 2018

SAM breaks its stereotype

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

mRNA 3'-UTR binding

determination method or standard

3 references

8 April 2019

SAM domains: uniform structure, diversity of function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Translational regulation and RNA localization in Drosophila oocytes and embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Translational repressors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

determination method or standard

1 reference

8 April 2019

Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

translation repressor activity

determination method or standard

3 references

31 January 2018

Translational regulation and RNA localization in Drosophila oocytes and embryos.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

31 January 2018

Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

translation repressor activity

determination method or standard

4 references

8 April 2019

Translational regulation and RNA localization in Drosophila oocytes and embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

determination method or standard

1 reference

31 January 2018

P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscular dystrophy pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

biological process

nuclear-transcribed mRNA poly(A) tail shortening

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

regulation of translation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

multicellular organism development

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

establishment of RNA localization

determination method or standard

1 reference

8 April 2019

Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

determination method or standard

1 reference

8 April 2019

Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscular dystrophy pathogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

negative regulation of translation

determination method or standard

5 references

31 January 2018

Translational regulation and RNA localization in Drosophila oocytes and embryos.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

31 January 2018

SAM domains: uniform structure, diversity of function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

31 January 2018

Translational repressors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

31 January 2018

Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q23972&geneProductId=UniProtKB:Q23972

determination method or standard

nuclear-transcribed mRNA poly(A) tail shortening

determination method or standard

3 references

8 April 2019

Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Rapid ATP-dependent deadenylation of nanos mRNA in a cell-free system from Drosophila embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

negative regulation of translation

determination method or standard

6 references

8 April 2019

SAM domains: uniform structure, diversity of function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Translational regulation and RNA localization in Drosophila oocytes and embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Translational repressors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

regulation of mRNA stability

determination method or standard

3 references

8 April 2019

SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q23972

determination method or standard

Smaug, PHAT analogous topology

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23972

sterile alpha motif domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23972

Protein Smaug, SAM domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q23972

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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