Proteomic profiling of acrolein adducts in human lung epithelial cells (Q28743757)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21704744

5 December 2024

Albert van der Vliet

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author name string

Bin Deng

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Page C. Spiess

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5 December 2024

Robert J. Hondal

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5 December 2024

Dwight E. Matthews

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5 December 2024

language of work or name

English

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publication date

19 October 2011

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17 June 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21704744

full work available at URL

5 December 2024

https://europepmc.org/articles/pmc3196826?pdf=render

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https://europepmc.org/articles/PMC3196826

5 December 2024

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https://europepmc.org/articles/PMC3196826?pdf=render

5 December 2024

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https://doi.org/10.1016/j.jprot.2011.05.039

5 December 2024

online access status

open access

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https://api.elsevier.com/content/article/PII:S1874391911002533?httpAccept=text/xml

5 December 2024

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Crossref

DOI

https://api.crossref.org/works/10.1016/J.JPROT.2011.05.039

https://api.elsevier.com/content/article/PII:S1874391911002533?httpAccept=text/plain

5 December 2024

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1016/J.JPROT.2011.05.039

Protein modification by acrolein: formation and stability of cysteine adducts

5 December 2024

published in

Journal of Proteomics

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2380-94

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cites work

1 reference

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Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair

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Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine

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HNE interacts directly with JNK isoforms in human hepatic stellate cells

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

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Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function

3 June 2018

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Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia

3 June 2018

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Systems analysis of protein modification and cellular responses induced by electrophile stress

3 June 2018

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15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue

3 June 2018

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Selenoproteins-What unique properties can arise with selenocysteine in place of cysteine?

3 June 2018

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Signaling pathways involved in phase II gene induction by alpha, beta-unsaturated aldehydes

3 June 2018

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Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: nucleophilic targets and adduct formation

3 June 2018

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Genome-wide transcriptional responses to acrolein

3 June 2018

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Proteomic profiling of rat lung epithelial cells induced by acrolein

3 June 2018

1 reference

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Glutathione-S-transferase P protects against endothelial dysfunction induced by exposure to tobacco smoke.

3 June 2018

1 reference

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The effects of acrolein on peroxiredoxins, thioredoxins, and thioredoxin reductase in human bronchial epithelial cells

3 June 2018

1 reference

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Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal

3 June 2018

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Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells

3 June 2018

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Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease

3 June 2018

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15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses.

3 June 2018

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Acrolein oxidizes the cytosolic and mitochondrial thioredoxins in human endothelial cells

3 June 2018

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Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion

3 June 2018

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Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein

3 June 2018

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Acrolein induces selective protein carbonylation in synaptosomes

3 June 2018

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Acrolein inhibits cytokine gene expression by alkylating cysteine and arginine residues in the NF-kappaB1 DNA binding domain

3 June 2018

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Estimating risk from ambient concentrations of acrolein across the United States.

3 June 2018

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GSH-dependent regulation of Fas-mediated caspase-8 activation by acrolein

3 June 2018

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15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors

3 June 2018

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Thioredoxin reductase is required for the inactivation of tumor suppressor p53 and for apoptosis induced by endogenous electrophiles

3 June 2018

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Semisynthesis and characterization of mammalian thioredoxin reductase

3 June 2018

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A sensitive method for the quantification of acrolein and other volatile carbonyls in ambient air.

3 June 2018

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SNOSID, a proteomic method for identification of cysteine S-nitrosylation sites in complex protein mixtures

3 June 2018

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Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione

3 June 2018

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Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.

3 June 2018

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Inhibition of NFkappaB activation and IL-8 expression in human bronchial epithelial cells by acrolein.

3 June 2018

1 reference

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Signaling kinases modulated by 4-hydroxynonenal.

3 June 2018

1 reference

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Proteins as biomarkers of oxidative/nitrosative stress in diseases: the contribution of redox proteomics

3 June 2018

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Reactions of 4-hydroxynonenal with proteins and cellular targets

3 June 2018

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Proteomic analysis of carbonylated proteins in two-dimensional gel electrophoresis using avidin-fluorescein affinity staining

3 June 2018

1 reference

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Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products

3 June 2018

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Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein

3 June 2018

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Determination of patterns of biologically relevant aldehydes in exhaled breath condensate of healthy subjects by liquid chromatography/atmospheric chemical ionization tandem mass spectrometry.

3 June 2018

1 reference

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Low-energy collision-induced dissociation fragmentation analysis of cysteinyl-modified peptides

3 June 2018

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Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications

3 June 2018

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Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis

3 June 2018

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The molecular effects of acrolein

3 June 2018

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Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity

3 June 2018

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Current status of acrolein as a lipid peroxidation product

3 June 2018

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Growth and differentiation of conducting airway epithelial cells in culture

3 June 2018

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Reactive oxygen-mediated protein oxidation in aging and disease

3 June 2018

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Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsatu

3 June 2018

1 reference

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Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases

3 June 2018

1 reference

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Actin Cys374 as a nucleophilic target of α,β-unsaturated aldehydes

3 June 2018

1 reference

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A sensitive method for the quantitative measurement of protein thiol modification in response to oxidative stress

27 November 2018

1 reference

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Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress.

27 November 2018

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Regulation of constitutive neutrophil apoptosis by the alpha,beta-unsaturated aldehydes acrolein and 4-hydroxynonenal

27 November 2018

1 reference

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The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway

27 November 2018

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Affinity chromatographic selection of carbonylated proteins followed by identification of oxidation sites using tandem mass spectrometry

27 November 2018

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High-performance liquid chromatography and capillary electrophoresis: methodological challenges for the determination of biologically relevant low-aliphatic aldehydes in human saliva

27 November 2018

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Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation

27 November 2018

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N(epsilon)-(3-methylpyridinium)lysine, a major antigenic adduct generated in acrolein-modified protein

27 November 2018

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Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid

27 November 2018

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Identification of protein carbonyls after two-dimensional electrophoresis

27 November 2018

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Alpha,beta-unsaturated aldehydes increase glutathione S-transferase mRNA and protein: correlation with activation of the antioxidant response element

27 November 2018

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Acrolein: a respiratory toxin that suppresses pulmonary host defense.

27 November 2018

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Proteomic mapping of 4-hydroxynonenal protein modification sites by solid-phase hydrazide chemistry and mass spectrometry

27 November 2018

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12 December 2020

Thioredoxin and thioredoxin reductase

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12 December 2020

Characterization of epitopes recognized by 4-hydroxy-2-nonenal specific antibodies

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12 December 2020

Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue

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12 December 2020

Acrolein causes inhibitor kappaB-independent decreases in nuclear factor kappaB activation in human lung adenocarcinoma (A549) cells

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12 December 2020

Comparison of the chemical properties of selenocysteine and selenocystine with their sulfur analogs

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12 December 2020

Synthetic organoselenium compounds as antioxidants: glutathione peroxidase activity

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5 December 2024

Identifiers

DOI

1 reference

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