High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes (Q28749562)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20488934%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20488934%20AND%20SRC:MED&resulttype=core&format=json

high-throughput sequencing

3 February 2020

main subject

1 reference

1 reference

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3 February 2020

Haig H Kazazian

1 reference

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3 February 2020

language of work or name

English

0 references

publication date

20 May 2010

1 reference

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3 February 2020

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3 February 2020

volume

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3 February 2020

issue

1 reference

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3 February 2020

page(s)

1262-1270

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20488934%20AND%20SRC:MED&resulttype=core&format=json

Complete Khoisan and Bantu genomes from southern Africa

3 February 2020

cites work

1 reference

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16 March 2017

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16 March 2017

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

16 March 2017

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16 March 2017

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16 March 2017

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16 March 2017

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16 March 2017

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16 March 2017

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Hot L1s account for the bulk of retrotransposition in the human population

16 March 2017

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Human population genetic structure and inference of group membership

16 March 2017

1 reference

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Length distribution of long interspersed nucleotide elements (LINEs) and processed pseudogenes of human endogenous retroviruses: implications for retrotransposition and pseudogene detection

16 March 2017

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Initial sequencing and comparative analysis of the mouse genome

16 March 2017

1 reference

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Genomic characterization of recent human LINE-1 insertions: evidence supporting random insertion

16 March 2017

1 reference

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Initial sequencing and analysis of the human genome

16 March 2017

1 reference

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Reading between the LINEs: human genomic variation induced by LINE-1 retrotransposition

16 March 2017

1 reference

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The distribution of human genetic diversity: a comparison of mitochondrial, autosomal, and Y-chromosome data

16 March 2017

1 reference

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Genetic traces of ancient demography

16 March 2017

1 reference

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An apportionment of human DNA diversity

16 March 2017

1 reference

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Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition

16 March 2017

1 reference

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Statistical method for testing the neutral mutation hypothesis by DNA polymorphism

16 March 2017

1 reference

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On the number of segregating sites in genetical models without recombination

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

L1 retrotransposition in human neural progenitor cells

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

LINE-mediated retrotransposition of marked Alu sequences

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Human L1 retrotransposition: cis preference versus trans complementation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Human LINE retrotransposons generate processed pseudogenes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

High frequency retrotransposition in cultured mammalian cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Mobile elements create structural variation: analysis of a complete human genome.

3 June 2018

1 reference

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Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition

3 June 2018

1 reference

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Identification and characterization of novel polymorphic LINE-1 insertions through comparison of two human genome sequence assemblies

3 June 2018

1 reference

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Long L1 insertions in human gene introns specifically reduce the content of corresponding primary transcripts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Molecular evolution and tempo of amplification of human LINE-1 retrotransposons since the origin of primates.

3 June 2018

1 reference

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Straightening out the LINEs: LINE-1 orthologous loci.

3 June 2018

1 reference

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Natural genetic variation caused by transposable elements in humans

3 June 2018

1 reference

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The insertional history of an active family of L1 retrotransposons in humans

3 June 2018

1 reference

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Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

SVA elements are nonautonomous retrotransposons that cause disease in humans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

ATLAS: a system to selectively identify human-specific L1 insertions.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Genome-wide targeted search for human specific and polymorphic L1 integrations

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

LINE-1 preTa elements in the human genome.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Tracing the LINEs of human evolution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

A comprehensive analysis of recently integrated human Ta L1 elements

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Adaptive evolution in LINE-1 retrotransposons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Analysis of the 5' junctions of R2 insertions with the 28S gene: implications for non-LTR retrotransposition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Maximum likelihood estimation of population parameters

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Defining the beginning and end of KpnI family segments

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Origin of the human L1 elements: proposed progenitor genes deduced from a consensus DNA sequence

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Unit-length line-1 transcripts in human teratocarcinoma cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Expression of a cytoplasmic LINE-1 transcript is regulated in a human teratocarcinoma cell line

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Isolation of an active human transposable element

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

L1 retrotransposition can occur early in human embryonic development.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Human population genetic structure and diversity inferred from polymorphic L1(LINE-1) and Alu insertions

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

SVA elements: a hominid-specific retroposon family.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928504

Estimating effective population size from samples of sequences: inefficiency of pairwise and segregating sites as compared to phylogenetic estimates

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20488934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

L1 (LINE-1) retrotransposon evolution and amplification in recent human history

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20488934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selection against deleterious LINE-1-containing loci in the human lineage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20488934

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GR.106419.110

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20488934%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20488934%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

20488934

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20488934%20AND%20SRC:MED&resulttype=core&format=json