A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models (Q28749085)

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Yaohuang Ke

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Yongke Zhang

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Qiu Yu

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Jonathan Lee

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Mingzhen Li

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Jialiang Song

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Jungang Chen

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Jihong Dai

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Fernando Jose Rebelo Do Couto

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Zhiqiang An

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Weimin Zhu

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Guo-Liang Yu

Creative Commons Attribution 4.0 International

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language of work or name

English

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publication date

5 February 2010

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e9072

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start time

5 February 2010

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysis

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Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials

20 June 2018

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20 June 2018

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Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab.

20 June 2018

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Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF.

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Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer

20 June 2018

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Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity

20 June 2018

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Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity

20 June 2018

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Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display

20 June 2018

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Complete inhibition of rhabdomyosarcoma xenograft growth and neovascularization requires blockade of both tumor and host vascular endothelial growth factor.

20 June 2018

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Veterinary sources of nonrodent monoclonal antibodies: interspecific and intraspecific hybridomas

20 June 2018

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20 June 2018

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Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

20 June 2018

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The impact of antigen density and antibody affinity on antibody-dependent cellular cytotoxicity: relevance for immunotherapy of carcinomas

20 June 2018

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Length distribution of CDRH3 in antibodies

20 June 2018

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Humanization of murine monoclonal antibodies through variable domain resurfacing

20 June 2018

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Anatomy of the antibody molecule

20 June 2018

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Immunoglobulin kappa light-chain diversity in rabbit is based on the 3' length heterogeneity of germ-line variable genes

20 June 2018

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Genomic organization and sequences of immunoglobulin light chain genes in a primitive vertebrate suggest coevolution of immunoglobulin gene organization

20 June 2018

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Humanization of a mouse monoclonal antibody by CDR–grafting: the importance of framework residues on loop conformation

20 June 2018

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Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma

20 June 2018

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Development of new rabbit monoclonal antibody to progesterone receptor (Clone SP2): no heat pretreatment but effective for paraffin section immunohistochemistry

20 June 2018

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Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia.

27 November 2018

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Coevolution of immunoglobulin heavy- and light-chain variable-region gene families

27 November 2018

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High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma

27 November 2018

1 reference

12 December 2020

Comparison of cell-surface human melanoma-associated antigens identified by rabbit and murine antibodies

1 reference

12 December 2020

Preparation and properties of monoclonal and polyclonal antibodies to mouse epidermal growth factor (EGF) receptors: evidence for cryptic EGF receptors in embryonal carcinoma cells

1 reference

12 December 2020

Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors

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12 December 2020

Determination of picomolar equilibrium dissociation constants in solution by enzyme-linked immunosorbent assay with fluorescence detection

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12 December 2020

10.1371/JOURNAL.PONE.0009072

Identifiers

DOI

1 reference

ADS bibcode

2010PLoSO...5.9072Y

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1 reference

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PubMed publication ID

20140208

1 reference