Linkage of bacterial protein synthesis and presentation of MHC class I-restricted Listeria monocytogenes-derived antigenic peptides (Q28731374)

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Simone Schenk

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Andreas Bubert

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Gernot Geginat

Creative Commons Attribution 4.0 International

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language of work or name

English

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publication date

2012

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e33335

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start time

12 March 2012

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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BAG-6 is essential for selective elimination of defective proteasomal substrates

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FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination

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Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

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Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action.

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Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products

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Protein synthesis upon acute nutrient restriction relies on proteasome function

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Quantifying the contribution of defective ribosomal products to antigen production: a model-based computational analysis

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Quantitating protein synthesis, degradation, and endogenous antigen processing

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Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

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Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

3 June 2018

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Enhanced intracellular dissociation of major histocompatibility complex class I-associated peptides: a mechanism for optimizing the spectrum of cell surface-presented cytotoxic T lymphocyte epitopes.

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Fibroblasts degrade newly synthesised collagen within the cell before secretion

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A deterministic model for the processing and presentation of bacteria-derived antigenic peptides.

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Role of tripeptidyl peptidase II in the processing of Listeria monocytogenes-derived MHC class I-presented antigenic peptides

21 January 2018

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Recognition of bacteria in the cytosol of Mammalian cells by the ubiquitin system

21 January 2018

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The major substrates for TAP in vivo are derived from newly synthesized proteins

21 January 2018

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Degradation of newly synthesized collagen

21 January 2018

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12 December 2020

Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies

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12 December 2020

CTL epitope generation is tightly linked to cellular proteolysis of a Listeria monocytogenes antigen

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12 December 2020

Intracellular rate-limiting steps in MHC class I antigen processing

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12 December 2020