Genetic and epigenetic fine mapping of causal autoimmune disease variants (Q28649603)

Markus Kleinewietfeld

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Nikolaos A. Patsopoulos

Nikolaos A Patsopoulos

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Mark J Daly

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David A. Hafler

David A Hafler

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Philip L. De Jager

Philip L De Jager

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Vijay Kuchroo

Vijay K Kuchroo

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Bradley Bernstein

Bradley E Bernstein

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author name string

Kyle Kai-How Farh

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Alexander Marson

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Jiang Zhu

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William J Housley

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Samantha Beik

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Noam Shoresh

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Holly Whitton

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Russell J H Ryan

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Alexander A Shishkin

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Meital Hatan

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Marlene J Carrasco-Alfonso

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Dita Mayer

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C John Luckey

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Charles B Epstein

Super-enhancers in the control of cell identity and disease

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language of work or name

English

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publication date

19 February 2015

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published in

Nature

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volume

518

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issue

7539

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page(s)

337-43

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cites work

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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

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Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

3 June 2018

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High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

3 June 2018

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EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation

3 June 2018

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3 June 2018

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3 June 2018

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Chromatin marks identify critical cell types for fine mapping complex trait variants

3 June 2018

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3 June 2018

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T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

3 June 2018

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STATs shape the active enhancer landscape of T cell populations

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3 June 2018

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3 June 2018

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Bayesian refinement of association signals for 14 loci in 3 common diseases

3 June 2018

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3 June 2018

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Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification

3 June 2018

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Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q

3 June 2018

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Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human

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3 June 2018

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Latent enhancers activated by stimulation in differentiated cells

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE13835

CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells.

21 January 2018

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Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25363779

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Isolation of mononuclear cells from tonsillar tissue

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25363779

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tests for Linear Trends in Proportions and Frequencies

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE13835

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE13835

1 reference

Dimensions Publication ID

1021809129

0 references

1 reference

1 reference

PubMed publication ID

25363779

1 reference