Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase (Q28646398)

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English	Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase	scientific journal article

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scholarly article

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PubMed publication ID

3 February 2017

Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase (English)

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PubMed publication ID

3 February 2017

phosphorylation

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author name string

M. R. Rani

1

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PubMed publication ID

3 February 2017

D. W. Leaman

2

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PubMed publication ID

3 February 2017

Y. Han

3

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PubMed publication ID

3 February 2017

S. Leung

4

1 reference

PubMed publication ID

3 February 2017

E. Croze

5

1 reference

PubMed publication ID

3 February 2017

E. N. Fish

6

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PubMed publication ID

3 February 2017

A. Wolfman

7

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PubMed publication ID

3 February 2017

R. M. Ransohoff

8

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PubMed publication ID

3 February 2017

language of work or name

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publication date

5 November 1999

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PubMed publication ID

3 February 2017

Journal of Biological Chemistry

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3 February 2017

274

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PubMed publication ID

3 February 2017

45

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PubMed publication ID

3 February 2017

32507–32511

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PubMed publication ID

3 February 2017

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

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https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Alpha and beta interferons and their receptor and their friends and relations.

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https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

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https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Shared receptor components but distinct complexes for alpha and beta interferons

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https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase

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https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Induction of beta-R1/I-TAC by interferon-beta requires catalytically active TYK2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Phosphatidylcholine breakdown and signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

The human type I interferon receptor. Identification of the interferon beta-specific receptor-associated phosphoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Inducible binding of a factor to the c-fos regulatory region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Interferon-α Engages the Insulin Receptor Substrate-1 to Associate with the Phosphatidylinositol 3′-Kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Role of STAT2 in the alpha interferon signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Function of Stat2 protein in transcriptional activation by alpha interferon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Differences in Activity between α and β Type I Interferons Explored by Mutational Analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32507

21 January 2018

Identifiers

10.1074/JBC.274.45.32507

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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