Editing of the HLA-DR-peptide repertoire by HLA-DM (Q28613148)

3 February 2017

title

Editing of the HLA-DR-peptide repertoire by HLA-DM (English)

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3 February 2017

H. Kropshofer

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3 February 2017

A. B. Vogt

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3 February 2017

G. Moldenhauer

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3 February 2017

J. Hammer

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3 February 2017

J. S. Blum

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3 February 2017

G. J. Hämmerling

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3 February 2017

language of work or name

English

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publication date

15 November 1996

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3 February 2017

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3 February 2017

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3 February 2017

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3 February 2017

page(s)

6144–6154

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The segment of invariant chain that is critical for association with major histocompatibility complex class II molecules contains the sequence of a peptide eluted from class II polypeptides

3 February 2017

cites work

1 reference

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Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

17 March 2017

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HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

17 March 2017

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An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

17 March 2017

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Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH

17 March 2017

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Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding

17 March 2017

1 reference

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DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

17 March 2017

1 reference

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HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

17 March 2017

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The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif

17 March 2017

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Mapping functional regions in the lumenal domain of the class II-associated invariant chain

17 March 2017

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Self-release of CLIP in peptide loading of HLA-DR molecules

17 March 2017

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The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

17 March 2017

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MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

17 March 2017

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A new human HLA class II-related locus, DM

17 March 2017

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HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

17 March 2017

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Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.

17 March 2017

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The generation of SDS-stable HLA DR dimers is independent of efficient peptide binding

3 June 2018

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Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum

3 June 2018

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Association between HLA-DM and HLA-DR in vivo

3 June 2018

1 reference

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Self-peptides from four HLA-DR alleles share hydrophobic anchor residues near the NH2-terminal including proline as a stop signal for trimming

3 June 2018

1 reference

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Promiscuous and allele-specific anchors in HLA-DR-binding peptides

3 June 2018

1 reference

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Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

3 June 2018

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MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

3 June 2018

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High-affinity binding of short peptides to major histocompatibility complex class II molecules by anchor combinations

3 June 2018

1 reference

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MHC class II function preserved by low-affinity peptide interactions preceding stable binding

3 June 2018

1 reference

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The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy

3 June 2018

1 reference

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Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA DM genes.

3 June 2018

1 reference

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Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

3 June 2018

1 reference

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In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides

3 June 2018

1 reference

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MHC ligands and peptide motifs: first listing

3 June 2018

1 reference

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Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

3 June 2018

1 reference

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The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.

3 June 2018

1 reference

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Mediation by HLA-DM of dissociation of peptides from HLA-DR

3 June 2018

1 reference

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Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR

3 June 2018

1 reference

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A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides

3 June 2018

1 reference

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Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

New class II-like genes in the murine MHC.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Identification of a motif for HLA-DR1 binding peptides using M13 display libraries

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Self-peptide released from class II HLA-DR1 exhibits a hydrophobic two-residue contact motif

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452435

Two populations of Ia-like molecules on a human B cell line.

3 June 2018

1 reference

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Intracellular transport of class II MHC molecules directed by invariant chain.

27 November 2018

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Self and foreign peptides interact with intact and disassembled MHC class II antigen HLA-DR via tryptophan pockets

27 November 2018

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Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens

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12 December 2020

Isolation and characterization of antigen-la complexes involved in T cell recognition

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12 December 2020

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

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12 December 2020