Crk activation of JNK via C3G and R-Ras (Q28609331)

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Crk activation of JNK via C3G and R-Ras (English)

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

N Mochizuki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Y Ohba

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

S Kobayashi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

N Otsuka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

A M Graybiel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

S Tanaka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

1 April 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 November 2019

published in

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

275

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

12667-12671

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

A novel viral oncogene with structural similarity to phospholipase C

6 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Role of Crk oncogene product in physiologic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Activation of R-Ras by Ras-Guanine Nucleotide-releasing Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Mitogenic and oncogenic properties of the small G protein Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

R-Ras is regulated by activators and effectors distinct from those that control Ras function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Chimeric proteins define variable and essential regions of Ha-ras-encoded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Signaling pathways in Ras-mediated tumorigenicity and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Efficient selection for high-expression transfectants with a novel eukaryotic vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Expression of mutated Nck SH2/SH3 adaptor respecifies mesodermal cell fate in Xenopus laevis development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Two species of human CRK cDNA encode proteins with distinct biological activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

C3G is tyrosine-phosphorylated after integrin-mediated cell adhesion in normal but not in Bcr/Abl expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

The functional role of CrkII in actin cytoskeleton organization and mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Integrin activation by R-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

The death effector domain of PEA-15 is involved in its regulation of integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Enhancement of Guanine-Nucleotide Exchange Activity of C3G for Rap1 by the Expression of Crk, CrkL, and Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12667

21 January 2018

Identifiers

DOI

10.1074/JBC.275.17.12667

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777559%20AND%20SRC:MED&resulttype=core&format=json