Bcl11b is required for differentiation and survival of αβ T lymphocytes (Q28592191)

31 January 2017

title

Bcl11b is required for differentiation and survival of alphabeta T lymphocytes (English)

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31 January 2017

Bcl11b is required for differentiation and survival of αβ T lymphocytes (English)

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B cell leukemia/lymphoma 11B

28 December 2023

main subject

lymphocyte

0 references

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GOA release 2020-03-11

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28 December 2023

Yukio Mishima

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31 January 2017

Yuichi Wakabayashi

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31 January 2017

Hisami Watanabe

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31 January 2017

Jun Inoue

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31 January 2017

Naoki Takeda

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31 January 2017

Jun Sakata

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31 January 2017

Jiro Hitomi

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31 January 2017

Takashi Yamamoto

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31 January 2017

Masanori Utsuyama

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31 January 2017

Ohtsura Niwa

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31 January 2017

Shinichi Aizawa

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31 January 2017

Ryo Kominami

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31 January 2017

language of work or name

English

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publication date

1 June 2003

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31 January 2017

28 April 2003

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717433

full work available at URL

28 December 2023

http://www.nature.com/articles/ni927.pdf

file format

Portable Document Format

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http://www.nature.com/articles/ni927

28 December 2023

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28 December 2023

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

533–539

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Natural and engineered disorders of lymphocyte development

31 January 2017

cites work

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Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

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An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

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Bclx regulates the survival of double-positive thymocytes

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

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COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein

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Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product

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Bcl11a is essential for normal lymphoid development

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

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c-kit+ stem cells and thymocyte precursors in the livers of adult mice

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Cell kinetic study of normal human bone marrow hematopoiesis and acute leukemia using 7AAD/PY

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Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

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7 January 2021

A nonredundant role for the adapter protein Shc in thymic T cell development

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The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

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7 January 2021

Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells

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Allelic loss mapping and physical delineation of a region harboring a putative thymic lymphoma suppressor gene on mouse chromosome 12

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7 January 2021

Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas

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7 January 2021

A matter of life and cell death

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7 January 2021

Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck

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