Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia (Q28590917)

31 January 2017

title

Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia (English)

1 reference

Polycystin 2, transient receptor potential cation channel

31 January 2017

main subject

1 reference

GOA release 2020-03-11

Ying Luo

1 reference

31 January 2017

Peter M. Vassilev

1 reference

31 January 2017

Xiaogang Li

1 reference

31 January 2017

Yoshifumi Kawanabe

1 reference

31 January 2017

Jing Zhou

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 April 2003

1 reference

Molecular and Cellular Biology

31 January 2017

published in

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

2600–2607

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

31 January 2017

cites work

1 reference

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Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease

17 March 2017

1 reference

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Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

The sequence, expression, and chromosomal localization of a novel polycystic kidney disease 1-like gene, PKD1L1, in human

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Polycystin-2 is an intracellular calcium release channel

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions

17 March 2017

1 reference

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Specific association of the gene product of PKD2 with the TRPC1 channel

17 March 2017

1 reference

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Identification of a human homologue of the sea urchin receptor for egg jelly: a polycystic kidney disease-like protein

17 March 2017

1 reference

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Identification of PKD2L, a human PKD2-related gene: tissue-specific expression and mapping to chromosome 10q25

17 March 2017

1 reference

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Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects

17 March 2017

1 reference

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Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

17 March 2017

1 reference

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PKD1 interacts with PKD2 through a probable coiled-coil domain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

17 March 2017

1 reference

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

17 March 2017

1 reference

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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

17 March 2017

1 reference

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Degradation of CFTR by the ubiquitin-proteasome pathway

7 April 2017

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The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance

7 April 2017

1 reference

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Voltage dependence and pH regulation of human polycystin-2-mediated cation channel activity

7 April 2017

1 reference

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Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Distinct subcellular expression of endogenous polycystin-2 in the plasma membrane and Golgi apparatus of MDCK cells

29 September 2017

1 reference

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Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization

29 September 2017

1 reference

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Identification and characterization of polycystin-2, the PKD2 gene product

29 September 2017

1 reference

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Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

29 September 2017

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Correcting temperature-sensitive protein folding defects

29 September 2017

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Identification and localization of polycystin, the PKD1 gene product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

29 September 2017

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Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease

3 June 2018

1 reference

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Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes

27 November 2018

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Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

27 November 2018

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Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=150742

Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2

27 November 2018

1 reference

12 December 2020

Measurement of cytosolic free Ca2+ with quin2

1 reference

12 December 2020

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

1 reference

12 December 2020

Cellular localization and tissue distribution of polycystin-1

1 reference

12 December 2020

10.1128/MCB.23.7.2600-2607.2003

Identifiers

DOI

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