Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis (Q28589322)

31 January 2017

title

Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis (English)

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31 January 2017

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GOA release 2020-03-11

Meis homeobox 1

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GOA release 2020-03-11

Paired box 6

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GOA release 2020-03-11

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Xin Zhang

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31 January 2017

Adam Friedman

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31 January 2017

Shaun Heaney

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31 January 2017

Patricia Purcell

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31 January 2017

Richard L. Maas

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31 January 2017

publication date

15 August 2002

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

2097–2107

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Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors

31 January 2017

cites work

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17 March 2017

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Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye

17 March 2017

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17 March 2017

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17 March 2017

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Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

17 March 2017

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BMP7 acts in murine lens placode development

17 March 2017

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Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila

17 March 2017

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Meis Proteins are Major In Vivo DNA Binding Partners for Wild-Type but Not Chimeric Pbx Proteins

17 March 2017

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Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development

17 March 2017

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Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly

17 March 2017

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Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans

17 March 2017

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17 March 2017

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Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice

17 March 2017

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

17 March 2017

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Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region

17 March 2017

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Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

17 March 2017

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Mouse small eye results from mutations in a paired-like homeobox-containing gene

17 March 2017

1 reference

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Xpbx1b and Xmeis1b play a collaborative role in hindbrain and neural crest gene expression in Xenopus embryos

7 April 2017

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The upstream ectoderm enhancer in Pax6 has an important role in lens induction

29 September 2017

1 reference

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Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye.

29 September 2017

1 reference

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The homeobox protein Six3 interacts with the Groucho corepressor and acts as a transcriptional repressor in eye and forebrain formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Reinventing a common strategy for patterning the eye.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Regulation of eye development by frizzled signaling in Xenopus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Expanded retina territory by midbrain transformation upon overexpression of Six6 (Optx2) in Xenopus embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).

29 September 2017

1 reference

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A highly conserved lens transcriptional control element from the Pax-6 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in patterning of the embryonic PNS.

29 September 2017

1 reference

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The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila

29 September 2017

1 reference

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The Rx homeobox gene is essential for vertebrate eye development

29 September 2017

1 reference

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Caution is advised when cDNA expression libraries are screened by southwestern methodologies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Identification of a new family of Pbx-related homeobox genes

29 September 2017

1 reference

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Developmental abnormalities in cultured mouse embryos deprived of retinoic by inhibition of yolk-sac retinol binding protein synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Small eye (Sey): a mouse model for the genetic analysis of craniofacial abnormalities.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Conserved regulation of proximodistal limb axis development by Meis1/Hth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

High conservation of cis-regulatory elements between quail and human for the Pax-6 gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

The Xenopus homologue of the Drosophila gene tailless has a function in early eye development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

wingless inhibits morphogenetic furrow movement in the Drosophila eye disc.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Fgf receptor signaling plays a role in lens induction.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Neural and head induction by insulin-like growth factor signals

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Aniridia-associated translocations, DNase hypersensitivity, sequence comparison and transgenic analysis redefine the functional domain of PAX6.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

lazarus is a novel pbx gene that globally mediates hox gene function in zebrafish

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Ectopic Sox3 activity elicits sensory placode formation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of the murine eye.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Pax6 induces ectopic eyes in a vertebrate

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Giant eyes in Xenopus laevis by overexpression of XOptx2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Efficient targeting of gene expression in chick embryos by microelectroporation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Signaling by the TGF-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Distinct cis-essential modules direct the time-space pattern of the Pax6 gene activity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Regulation of Pax6 expression is conserved between mice and flies.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Induction of lens differentiation by activation of a bZIP transcription factor, L-Maf

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Ectopic lens induction in fish in response to the murine homeobox gene Six3.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Forebrain and midbrain regions are deleted in Otx2−/− mutants due to a defective anterior neuroectoderm specification during gastrulation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=186446

Hox proteins meet more partners

27 November 2018

1 reference

12 December 2020

Dosage requirement and allelic expression of PAX6 during lens placode formation

1 reference

12 December 2020

Meis family proteins are required for hindbrain development in the zebrafish

1 reference

12 December 2020

Uchida rat (rSey): a new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.1007602

1 reference

1 reference

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