Aminophosphinic inhibitors as transition state analogues of enkephalin-degrading enzymes: a class of central analgesics (Q28588212)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

Aminophosphinic inhibitors as transition state analogues of enkephalin-degrading enzymes: a class of central analgesics (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

Membrane metallo endopeptidase

4 December 2019

main subject

enkephalin

0 references

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

H Chen

1 reference

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4 December 2019

P Coric

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

M C Fournie-Zaluski

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

B P Roques

series ordinal

1 reference

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4 December 2019

language of work or name

English

0 references

publication date

1 September 1998

1 reference

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4 December 2019

number of pages

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

2 references

31 January 2017

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4 December 2019

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

page(s)

12028-12033

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin

4 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines

17 March 2017

1 reference

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Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Neutral endopeptidase 24.11: structure, inhibition, and experimental and clinical pharmacology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Analgesic effects of kelatorphan, a new highly potent inhibitor of multiple enkephalin degrading enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Autoradiographic comparison of the distribution of the neutral endopeptidase "enkephalinase" and of mu and delta opioid receptors in rat brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Potent antinociceptive effects of kelatorphan (a highly efficient inhibitor of multiple enkephalin-degrading enzymes) systemically administered in normal and arthritic rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Inhibition of the enkephalin-metabolizing enzymes by the first systemically active mixed inhibitor prodrug RB 101 induces potent analgesic responses in mice and rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

"Mixed inhibitor-prodrug" as a new approach toward systemically active inhibitors of enkephalin-degrading enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

The dual peptidase inhibitor RB101 induces a long-lasting increase in the extracellular level of Met-enkephalin-like material in the nucleus accumbens of freely moving rats

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

In vitro and in vivo effects of kelatorphan on enkephalin metabolism in rodent brain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

1H NMR configurational correlation for retro-inverso dipeptides: application to the determination of the absolute configuration of "enkephalinase" inhibitors. Relationships between stereochemistry and enzyme recognition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Lack of significant changes in mu, delta opioid binding sites and neutral endopeptidase EC 3.4.24.11 in the brain and spinal cord of arthritic rats

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Analgesic responses elicited by endogenous enkephalins (protected by mixed peptidase inhibitors) in a variety of morphine-sensitive noxious tests.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Lack of physical dependence in mice after repeated systemic administration of the mixed inhibitor prodrug of enkephalin-degrading enzymes, RB101

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

In vivo occupation of mouse brain opioid receptors by endogenous enkephalins: blockade of enkephalin degrading enzymes by RB 101 inhibits [3H]diprenorphine binding

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

The structure of bestatin

3 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21759

3 June 2018

https://api.crossref.org/works/10.1073%2FPNAS.95.20.12028

Dns-Gly-(p-NO2)Phe-beta Ala, a specific fluorogenic substrate for neutral endopeptidase 24.11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.20.12028

Effects of opioids and non-opioids on c-Fos-like immunoreactivity induced in rat lumbar spinal cord neurons by noxious heat stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.20.12028

Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.20.12028

New kelatorphan-related inhibitors of enkephalin metabolism: improved antinociceptive properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.20.12028

Exploration of neutral endopeptidase active site by a series of new thiol-containing inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.20.12028

Assessment of endogenous enkephalins efficacy in the hot plate test in mice: comparative study with morphine

21 January 2018

1 reference

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Effects of Kelatorphan and morphine before and after noxious stimulation on immediate-early gene expression in rat spinal cord neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.20.12028

Effects of kelatorphan and other peptidase inhibitors on the in vitro and in vivo release of methionine-enkephalin-like material from the rat spinal cord

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/9751784

12 December 2020

inferred from PubMed ID database lookup

A simplified method of evaluating dose-effect experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/9751784

12 December 2020

inferred from PubMed ID database lookup

[A fluorimetric method for the determination of brain aminopeptidases]

1 reference

https://pubmed.ncbi.nlm.nih.gov/9751784

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.95.20.12028

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9751784%20AND%20SRC:MED&resulttype=core&format=json