p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication (Q28587920)

31 January 2017

title

p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication (English)

1 reference

Myelocytomatosis oncogene

31 January 2017

main subject

1 reference

Mitogen-activated protein kinase 14

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Matthias Gaestel

0 references

Ian G. Cannell

0 references

Martin Eilers

0 references

Yi W. Kong

1 reference

31 January 2017

Samantha J. Johnston

1 reference

31 January 2017

Melissa L. Chen

1 reference

31 January 2017

Hilary M. Collins

1 reference

31 January 2017

Helen C. Dobbyn

1 reference

31 January 2017

Androulla Elia

1 reference

31 January 2017

Theresia R. Kress

1 reference

31 January 2017

Martin Dickens

1 reference

31 January 2017

Michael J. Clemens

1 reference

31 January 2017

David M. Heery

1 reference

31 January 2017

Anne E. Willis

1 reference

31 January 2017

Martin Bushell

1 reference

31 January 2017

language of work or name

English

0 references

publication date

23 March 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 January 2017

published in

1 reference

31 January 2017

volume

107

1 reference

31 January 2017

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31 January 2017

page(s)

5375–5380

1 reference

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

31 January 2017

cites work

1 reference

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Non-transcriptional control of DNA replication by c-Myc

17 March 2017

1 reference

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A microRNA component of the p53 tumour suppressor network

17 March 2017

1 reference

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Regulation of protein synthesis by inducible wild-type p53 in human lung carcinoma cells

17 March 2017

1 reference

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MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

17 March 2017

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif

17 March 2017

1 reference

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Facilitating replication under stress: an oncogenic function of MYC?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Non-classical p38 map kinase functions: cell cycle checkpoints and survival

29 September 2017

1 reference

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A microRNA DNA methylation signature for human cancer metastasis

29 September 2017

1 reference

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The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene

29 September 2017

1 reference

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c-MYC protein is degraded in response to UV irradiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Control of cellular senescence by CPEB

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Transcriptional regulation and transformation by Myc proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

The DNA damage response: sensing and signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Ser392 phosphorylation regulates the oncogenic function of mutant p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Chromosomal translocations in leukaemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Detection of S-phase cell cycle progression using 5-ethynyl-2'-deoxyuridine incorporation with click chemistry, an alternative to using 5-bromo-2'-deoxyuridine antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

DNA damage, c-myc suppression and apoptosis induced by the novel topoisomerase II inhibitor, salvicine, in human breast cancer MCF-7 cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

c-Myc degradation induced by DNA damage results in apoptosis of CHO cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851793

How do microRNAs regulate gene expression?

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20212154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20212154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcription - guarding the genome by sensing DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20212154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0910015107

1 reference

ADS bibcode

2010PNAS..107.5375C

0 references

1 reference

1 reference

1 reference