Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism (Q28586519)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16734431%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16734431%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

0 references

1 reference

GOA release 2020-03-11

1 reference

1 reference

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28 January 2020

1 reference

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28 January 2020

Robert L Nussbaum

1 reference

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28 January 2020

Ingrid Pribill

2 references

31 January 2017

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28 January 2020

Mikhail Y Golovko

1 reference

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28 January 2020

Thad A Rosenberger

1 reference

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28 January 2020

Nils J Faergeman

1 reference

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28 January 2020

Nelson B Cole

1 reference

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28 January 2020

Eric J Murphy

1 reference

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28 January 2020

language of work or name

English

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publication date

1 June 2006

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28 January 2020

2 references

31 January 2017

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28 January 2020

2 references

31 January 2017

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28 January 2020

2 references

31 January 2017

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28 January 2020

page(s)

6956-6966

1 reference

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Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein

28 January 2020

cites work

1 reference

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Alpha-synuclein gene deletion decreases brain palmitate uptake and alters the palmitate metabolism in the absence of alpha-synuclein palmitate binding

17 March 2017

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Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases

17 March 2017

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Brain arachidonic acid incorporation is decreased in heart fatty acid binding protein gene-ablated mice

17 March 2017

1 reference

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Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism

17 March 2017

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Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice

17 March 2017

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Fluorescence studies suggest a role for alpha-synuclein in the phosphatidylinositol lipid signaling pathway

17 March 2017

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Acyl-CoA synthetase 2 overexpression enhances fatty acid internalization and neurite outgrowth

17 March 2017

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alpha-Synuclein locus triplication causes Parkinson's disease

17 March 2017

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Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase

17 March 2017

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Altered Fatty Acid Composition of Dopaminergic Neurons Expressing α-Synuclein and Human Brains with α-Synucleinopathies

17 March 2017

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A simple method for the isolation and purification of total lipides from animal tissues

17 March 2017

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Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease

17 March 2017

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Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

17 March 2017

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Characterization of mouse homolog of brain acyl-CoA hydrolase: molecular cloning and neuronal localization

17 March 2017

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Mouse fatty acid transport protein 4 (FATP4): characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase

17 March 2017

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Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

17 March 2017

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Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

17 March 2017

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A novel acyl-CoA synthetase, ACS5, expressed in intestinal epithelial cells and proliferating preadipocytes

17 March 2017

1 reference

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L-FABP and I-FABP expression increase NBD-stearate uptake and cytoplasmic diffusion in L cells

17 March 2017

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

17 March 2017

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A novel arachidonate-preferring acyl-CoA synthetase is present in steroidogenic cells of the rat adrenal, ovary, and testis

17 March 2017

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Molecular characterization and expression of rat acyl-CoA synthetase 3

17 March 2017

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Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB

17 March 2017

1 reference

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Discovery of an arachidonoyl coenzyme A synthetase in human platelets

17 March 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

17 March 2017

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

17 March 2017

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

7 April 2017

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

7 April 2017

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Alternative promotion of the mouse acyl-CoA synthetase 6 (mAcsl6) gene mediates the expression of multiple transcripts with 5'-end heterogeneity: genetic organization of mAcsl6 variants.

7 April 2017

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Synaptic lipid signaling: significance of polyunsaturated fatty acids and platelet-activating factor

29 September 2017

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Human brain acyl-CoA hydrolase isoforms encoded by a single gene

29 September 2017

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Demonstration of alpha-synuclein immunoreactivity in neuronal and glial cytoplasm in normal human brain tissue using proteinase K and formic acid pretreatment

29 September 2017

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Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

29 September 2017

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alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

29 September 2017

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Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

29 September 2017

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29 September 2017

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Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins

29 September 2017

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Liver fatty acid-binding protein expression in transfected fibroblasts stimulates fatty acid uptake and metabolism

29 September 2017

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Identification of two distinct synucleins from human brain

29 September 2017

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The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

29 September 2017

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Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

29 September 2017

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Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

29 September 2017

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Modulation of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/quisqualate receptors by phospholipase A2: a necessary step in long-term potentiation?

29 September 2017

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Sensitive titration microcalorimetric study of the binding of Salmonella O-antigenic oligosaccharides by a monoclonal antibody

29 September 2017

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40 Determination of the positional distribution of fatty acids in glycerolipids

29 September 2017

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Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans

29 September 2017

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Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease

3 June 2018

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Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

3 June 2018

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Evidence for a single non-arachidonic acid-specific fatty acyl-CoA synthetase in heart which is regulated by Mg2+

3 June 2018

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Intestinal and liver fatty acid binding proteins differentially affect fatty acid uptake and esterification in L-cells

3 June 2018

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Cell and tissue distribution and developmental change of neuron specific 14 kDa protein (phosphoneuroprotein 14)

3 June 2018

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Changes in free fatty acids of brain by drug-induced convulsions, electroshock and anaesthesia

3 June 2018

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Cerebral metabolism of plasma [14C]palmitate in awake, adult rat: Subcellular localization

3 June 2018

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Utilization of plasma fatty acid in rat brain: distribution of [14C]palmitate between oxidative and synthetic pathways

3 June 2018

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Fatty acid incorporation is decreased in astrocytes cultured from alpha-synuclein gene-ablated mice

3 June 2018

1 reference

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Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice.

27 November 2018

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Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast

27 November 2018

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Characterization of recombinant long-chain rat acyl-CoA synthetase isoforms 3 and 6: identification of a novel variant of isoform 6.

27 November 2018

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In vivo imaging detects a transient increase in brain arachidonic acid metabolism: a potential marker of neuroinflammation

27 November 2018

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An improved method for tissue long-chain acyl-CoA extraction and analysis

27 November 2018

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Heart fatty acid uptake is decreased in heart fatty acid-binding protein gene-ablated mice.

27 November 2018

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Structural determinants of PLD2 inhibition by alpha-synuclein

27 November 2018

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Rat brain arachidonic acid metabolism is increased by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide

27 November 2018

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Yeast cells provide insight into alpha-synuclein biology and pathobiology

27 November 2018

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The induction of amyloid precursor protein and alpha-synuclein in rat hippocampal astrocytes by diethyldithiocarbamate and copper with or without glutathione

27 November 2018

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Characterization of the Acyl-CoA synthetase activity of purified murine fatty acid transport protein 1.

27 November 2018

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Brain lipid metabolism in the cPLA2 knockout mouse

27 November 2018

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Rapid synthesis and turnover of brain microsomal ether phospholipids in the adult rat.

27 November 2018

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Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins.

27 November 2018

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Membrane binding and self-association of alpha-synucleins.

27 November 2018

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Phospholipase A2 mediates ischemic injury in the hippocampus: a regional difference of neuronal vulnerability

27 November 2018

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Delivery and turnover of plasma-derived essential PUFAs in mammalian brain.

27 November 2018

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Subcellular localization of alpha-synuclein in primary neuronal cultures: effect of missense mutations

27 November 2018

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Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase.

27 November 2018

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alpha-synuclein is developmentally expressed in cultured rat brain oligodendrocytes.

27 November 2018

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Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions

27 November 2018

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Degenerative terminals of the perforant pathway are human alpha-synuclein-immunoreactive in the hippocampus of patients with diffuse Lewy body disease

27 November 2018

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Abnormal distribution of the non-Abeta component of Alzheimer's disease amyloid precursor/alpha-synuclein in Lewy body disease as revealed by proteinase K and formic acid pretreatment

27 November 2018

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Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

27 November 2018

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Thermodynamics of Ligand Binding to Acyl-Coenzyme A Binding Protein Studied by Titration Calorimetry†

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532510

Analysis of the ligand binding properties of recombinant bovine liver-type fatty acid binding protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2532510

Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments

27 November 2018

1 reference

12 December 2020

Intravenously injected [1-14C]arachidonic acid targets phospholipids, and [1-14C]palmitic acid targets neutral lipids in hearts of awake rats

1 reference

12 December 2020

alpha-Synuclein membrane interactions and lipid specificity

1 reference

12 December 2020

Initial incorporation into rat liver glycerolipids of intraportally injected [3H]glycerol

1 reference

12 December 2020

Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus

1 reference

12 December 2020

A quantitative method for measuring regional in vivo fatty-acid incorporation into and turnover within brain phospholipids: review and critical analysis

1 reference

12 December 2020

Purification, properties, and specificity of rat brain cytosolic fatty acyl coenzyme A hydrolase

1 reference

12 December 2020

Long-term potentiation requires activation of calcium-independent phospholipase A2

1 reference

12 December 2020

Biochemical studies of two rat acyl-CoA synthetases, ACS1 and ACS2

1 reference

12 December 2020

Fatty acid binding protein: stimulation of microsomal phosphatidic acid formation

1 reference

12 December 2020

Identifiers

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16734431%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16734431%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16734431%20AND%20SRC:MED&resulttype=core&format=json