Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo (Q28586128)

23 June 2017

title

Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo (English)

1 reference

23 June 2017

main subject

Homeobox protein Hox-A1

1 reference

GOA release 2020-03-11

Anthony Gavalas

0 references

Sophie Remacle

1 reference

23 June 2017

Leïla Abbas

1 reference

23 June 2017

Olivier De Backer

1 reference

23 June 2017

Nathalie Pacico

1 reference

23 June 2017

Françoise Gofflot

1 reference

23 June 2017

René Rezsöhazy

1 reference

23 June 2017

Jacques J Picard

1 reference

23 June 2017

language of work or name

English

0 references

publication date

1 October 2004

1 reference

Molecular and Cellular Biology

23 June 2017

published in

1 reference

23 June 2017

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23 June 2017

1 reference

23 June 2017

page(s)

8567-8575

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In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster

23 June 2017

cites work

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17 March 2017

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Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton

17 March 2017

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17 March 2017

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17 March 2017

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Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy

17 March 2017

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17 March 2017

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Distinct HOX N-terminal arm residues are responsible for specificity of DNA recognition by HOX monomers and HOX.PBX heterodimers

17 March 2017

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17 March 2017

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Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

17 March 2017

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Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox

17 March 2017

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17 March 2017

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Changing homeodomain residues 2 and 3 of Hoxa1 alters its activity in a cell-type and enhancer dependent manner

29 September 2017

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29 September 2017

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Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteins

29 September 2017

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An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif

29 September 2017

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Regulation of Cre recombinase activity by the synthetic steroid RU 486.

29 September 2017

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Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif

29 September 2017

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The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1.

29 September 2017

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Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain.

29 September 2017

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29 September 2017

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Segmentation and specification in the branchial region of the head: the role of the Hox selector genes

29 September 2017

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Hox genes and mammalian development.

3 June 2018

1 reference

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Developmental functions of mammalian Hox genes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Insertion of a targeting construct in a Hoxd-10 allele can influence the control of Hoxd-9 expression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Expression of the mouse labial-like homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain

3 June 2018

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Domains of cellular retinoic acid-binding protein I (CRABP I) expression in the hindbrain and neural crest of the mouse embryo

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

The Hexapeptide and Linker Regions of the AbdA Hox Protein Regulate Its Activating and Repressive Functions

3 June 2018

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Eliminating zebrafish pbx proteins reveals a hindbrain ground state.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Targeted insertion results in a rhombomere 2-specific Hoxa2 knockdown and ectopic activation of Hoxa1 expression.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Genetic patterning of the posterior neuropore region of curly tail mouse embryos: deficiency of Wnt5a expression.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Cross-regulatory interactions between Hox genes and the control of segmental expression in the vertebrate central nervous system.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

extradenticle raises the DNA binding specificity of homeotic selector gene products

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=516739

Two rhombomeres are altered in Hoxa-1 mutant mice

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15367676

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.24.19.8567-8575.2004

1 reference

OpenCitations bibliographic resource ID

23 June 2017

4639343

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4639343

1 reference