Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion (Q28577458)

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English	Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion	scientific journal article

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PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788770%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion (English)

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788770%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

colorectal cancer

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based on heuristic

inferred from title

colorectal carcinoma

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based on heuristic

inferred from title

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788770%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Nicolas X Tritsch

3

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10 January 2020

author name string

Masoud Shekarabi

1

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31 January 2017

Europe PubMed Central

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10 January 2020

Jean-Francois Bouchard

5

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31 January 2017

Europe PubMed Central

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10 January 2020

Stephen J Morris

4

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10 January 2020

Timothy E Kennedy

6

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10 January 2020

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publication date

1 March 2005

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10 January 2020

Journal of Neuroscience

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31 January 2017

Europe PubMed Central

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10 January 2020

25

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PubMed publication ID

31 January 2017

Europe PubMed Central

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10 January 2020

12

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788770%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

3132-3141

1 reference

Europe PubMed Central

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10 January 2020

The Drosophila SH2-SH3 adapter protein Dock is expressed in embryonic axons and facilitates synapse formation by the RP3 motoneuron

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mena is required for neurulation and commissure formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth cone guidance: first steps towards a deeper understanding

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pak to the future

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of p21-activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of neural Wiskott-Aldrich syndrome protein in neurite extension in PC12 cells and rat hippocampal primary culture cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How WASP regulates actin polymerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular mechanisms of netrin function: long-range and short-range actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal and spatial distribution of activated Pak1 in fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho GTPases in growth cone guidance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread expression of netrin-1 by neurons and oligodendrocytes in the adult mammalian spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A WASp-VASP complex regulates actin polymerization at the plasma membrane.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho family proteins: coordinating cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling to the Rho GTPases: networking with the DH domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dominant-negative p65 PAK peptide inhibits angiogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acidic regions of WASp and N-WASP can synergize with CDC42Hs and Rac1 to induce filopodia and lamellipodia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of semaphorin signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

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Where the rubber meets the road: netrin expression and function in developing and adult nervous systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of axon guidance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of filopodia initiation by reorganization of a dendritic network

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

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Formation of filopodia-like bundles in vitro from a dendritic network

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of the p21-activated kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial morphogenesis: Netrin comes to a sticky and terminal end.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain meets pancreas: netrin, an axon guidance molecule, controls epithelial cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caenorhabditis elegans WASP and Ena/VASP proteins play compensatory roles in morphogenesis and neuronal cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase in netrin-1 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of FAK and Src are receptor-proximal events required for netrin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a mouse p21Cdc42/Rac activated kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Making the connection: Cytoskeletal rearrangements during growth cone guidance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoskeletal events in growth cone steering

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

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Myosin drives retrograde F-actin flow in neuronal growth cones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidance of circumferentially growing axons by netrin-dependent and -independent floor plate chemotropism in the vertebrate brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth cone form is behavior-specific and, consequently, position-specific along the retinal axon pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-dependent growth cone guidance by netrin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho GTPases and the actin cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simplified system for generating recombinant adenoviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15788770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1920-04.2005

2 references

Consolidated OpenCitations Corpus – April 2017

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10 January 2020

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Consolidated OpenCitations Corpus – April 2017

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10 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788770%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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