MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin (Q28576622)

31 January 2017

title

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin (English)

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PubMed

31 January 2017

X. Nan

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A. Bird

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F. J. Campoy

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31 January 2017

language of work or name

English

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publication date

21 February 1997

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PubMed

31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

471–481

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PubMed

Specific protection of methylated CpGs in mammalian nuclei

31 January 2017

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DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

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Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene

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Binding of histone H1 to DNA is indifferent to methylation at CpG sequences

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Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro

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Active repression mechanisms of eukaryotic transcription repressors

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Absence of somatic histone H1 in oocytes and preblastula embryos of Xenopus laevis

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Dependence of transcriptional repression on CpG methylation density

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A protein from human placental nuclei binds preferentially to 5-methylcytosine-rich DNA

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Transcriptional repression by methylation: cooperativity between a CpG cluster in the promoter and remote CpG-rich regions

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The effect of histone H1 and DNA methylation on transcription

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7 January 2021

The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated nonspecific DNA sequences

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Inactive chromatin spreads from a focus of methylation

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Effect of regional DNA methylation on gene expression

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Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II

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Inhibition of promoter activity by methylation: possible involvement of protein mediators

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Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

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GAL4 derivatives function alone and synergistically with mammalian activators in vitro

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Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

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A bacteriophage RNA polymerase transcribes in vitro through a nucleosome core without displacing it.

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A preference of histone H1 for methylated DNA.

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Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

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Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

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7 January 2021

Site specific demethylation in the promoter of human gamma-globin gene does not alleviate methylation mediated suppression.

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7 January 2021

Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

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7 January 2021

DNA methylation specifies chromosomal localization of MeCP2.

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7 January 2021

Methylation at CpG sequences does not influence histone H1 binding to a nucleosome including a Xenopus borealis 5 S rRNA gene

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X-chromosome inactivation and cell memory

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In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells

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7 January 2021

Chromatin structure and RNA polymerase II connection: implications for transcription

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7 January 2021

The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse.

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7 January 2021

Methylation of genomes and genes at the invertebrate-vertebrate boundary

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7 January 2021

Expression of a cloned adenovirus gene is inhibited by in vitro methylation

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7 January 2021

Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

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7 January 2021

10.1016/S0092-8674(00)81887-5

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017