CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling (Q28567160)

31 January 2017

title

CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling (English)

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Protein tyrosine phosphatase, receptor type, C

31 January 2017

main subject

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GOA release 2020-03-11

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Claudine Irles

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31 January 2017

Antony Symons

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31 January 2017

Frédérique Michel

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31 January 2017

Talitha R. Bakker

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31 January 2017

P. Anton van der Merwe

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31 January 2017

language of work or name

English

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publication date

1 February 2003

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

189–197

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S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

31 January 2017

cites work

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Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

21 January 2018

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Positive and negative regulation of Src-family membrane kinases by CD45.

21 January 2018

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Structures of Src-family tyrosine kinases

21 January 2018

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Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

21 January 2018

1 reference

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

21 January 2018

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Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

21 January 2018

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Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts

21 January 2018

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Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains

21 January 2018

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Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.

21 January 2018

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Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

21 January 2018

1 reference

Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain

21 January 2018

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The structure and ligand interactions of CD2: implications for T-cell function

21 January 2018

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CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development

21 January 2018

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Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1

21 January 2018

1 reference

Biochemical association of CD45 with the T cell receptor complex: regulation by CD45 isoform and during T cell activation

21 January 2018

1 reference

Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction

21 January 2018

1 reference

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

21 January 2018

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Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

21 January 2018

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Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

21 January 2018

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Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.

21 January 2018

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Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

21 January 2018

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The leukocyte common antigen family

21 January 2018

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Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase

21 January 2018

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Raft membrane domains and immunoreceptor functions

21 January 2018

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Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling

21 January 2018

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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

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Lipid domain structure of the plasma membrane revealed by patching of membrane components

21 January 2018

1 reference

Second cysteine-rich region of epidermal growth factor receptor contains targeting information for caveolae/rafts

21 January 2018

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N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae

21 January 2018

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Microdomain-dependent regulation of Lck and Fyn protein-tyrosine kinases in T lymphocyte plasma membranes

21 January 2018

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Relationship of lipid rafts to transient confinement zones detected by single particle tracking

21 January 2018

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Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes

21 January 2018

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Lipid rafts mediate biosynthetic transport to the T lymphocyte uropod subdomain and are necessary for uropod integrity and function

21 January 2018

1 reference

The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells

21 January 2018

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O-linked glycans mediate apical sorting of human intestinal sucrase-isomaltase through association with lipid rafts

21 January 2018

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Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck

21 January 2018

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CD28 affects the earliest signaling events generated by TCR engagement

21 January 2018

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Regulation of Lck activity by CD4 and CD28 in the immunological synapse

21 January 2018

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A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila

21 January 2018

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An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

21 January 2018

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Structural study of the O-linked sugar chains of human leukocyte tyrosine phosphatase CD45

21 January 2018

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Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

21 January 2018

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The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

21 January 2018

1 reference

7 January 2021

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

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7 January 2021

Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains

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7 January 2021

The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation

1 reference

7 January 2021

The EGF receptor: a nexus for trafficking and signaling

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7 January 2021