Adrenoceptor alpha 2A (Q28558049)

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mammalian protein found in Rattus norvegicus

alpha-2A adrenoceptor
alpha-2A adrenergic receptor
alpha-2AAR
adrenergic receptor, alpha 2a
alpha-2A adrenoreceptor
Adra2a
alpha-2D adrenergic receptor
adrenergic, alpha-2A-, receptor

Language	Label	Description	Also known as
English	Adrenoceptor alpha 2A	mammalian protein found in Rattus norvegicus	alpha-2A adrenoceptor alpha-2A adrenergic receptor alpha-2AAR adrenergic receptor, alpha 2a alpha-2A adrenoreceptor Adra2a alpha-2D adrenergic receptor adrenergic, alpha-2A-, receptor

Statements

1 reference

25 May 2022

UniProt protein ID

Alpha 2A adrenoceptor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22909

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method or standard

1 reference

14 February 2019

Alpha-adrenergic receptor (alpha(2 A )) is colocalized in basal forebrain cholinergic neurons: a light and electron microscopic double immunolabeling study

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

plasma membrane

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

14 February 2019

Alpha-adrenergic receptor (alpha(2 A )) is colocalized in basal forebrain cholinergic neurons: a light and electron microscopic double immunolabeling study

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

14 February 2019

Synergistic effect of fibroblast growth factor-4 in ectopic bone formation induced by bone morphogenetic protein-2

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

14 February 2019

Alpha-2A-adrenergic receptors are present on neurons in the central nucleus of the amygdala that project to the dorsal vagal complex in the rat

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

integral component of plasma membrane

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

determination method or standard

1 reference

14 February 2019

alpha(2a) and alpha(2c) adrenoceptors on spinal neurons controlling penile erection

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

determination method or standard

1 reference

14 February 2019

alpha(2a) and alpha(2c) adrenoceptors on spinal neurons controlling penile erection

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

determination method or standard

1 reference

14 February 2019

Alpha-adrenergic receptor (alpha(2 A )) is colocalized in basal forebrain cholinergic neurons: a light and electron microscopic double immunolabeling study

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

glutamatergic synapse

determination method or standard

2 references

GABA-ergic synapse

determination method or standard

1 reference

14 February 2019

Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

integral component of postsynaptic membrane

determination method or standard

2 references

integral component of presynaptic active zone membrane

determination method or standard

1 reference

14 February 2019

Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

integral component of postsynaptic density membrane

determination method or standard

1 reference

14 February 2019

Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

biological process

acute inflammatory response

determination method or standard

1 reference

14 February 2019

Antagonism of alpha2A-adrenoceptor: a novel approach to inhibit inflammatory responses in sepsis

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

DNA replication

determination method or standard

1 reference

14 February 2019

Transiently overexpressed alpha2-adrenoceptors and their control of DNA synthesis in the developing brain

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

regulation of smooth muscle contraction

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

G protein-coupled receptor signaling pathway

determination method or standard

3 references

14 February 2019

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

female pregnancy

determination method or standard

1 reference

14 February 2019

The roles of alpha2-adrenoceptor subtypes in the control of cervical resistance in the late-pregnant rat

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

regulation of vasoconstriction

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

platelet activation

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

glucose homeostasis

determination method or standard

1 reference

14 February 2019

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

negative regulation of calcium ion-dependent exocytosis

determination method or standard

1 reference

14 February 2019

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

determination method or standard

1 reference

14 February 2019

The transient receptor potential channel TRPM8 is inhibited via the alpha 2A adrenoreceptor signaling pathway

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

negative regulation of insulin secretion involved in cellular response to glucose stimulus

determination method or standard

1 reference

14 February 2019

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

negative regulation of uterine smooth muscle contraction

determination method or standard

1 reference

14 February 2019

Different roles of alpha2-adrenoceptor subtypes in non-pregnant and late-pregnant uterine contractility in vitro in the rat

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

adenylate cyclase-activating adrenergic receptor signaling pathway

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22909

determination method or standard

GPCR, rhodopsin-like, 7TM

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P22909

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSRNOP00000066242

1 reference

ensembl Release 106

Ensembl protein ID

ENSRNOP00000066242

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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