Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats (Q28538103)

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scientific article (publication date: 2014)

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English	Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats	scientific article (publication date: 2014)

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scholarly article

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15 March 2020

Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats (English)

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15 March 2020

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15 March 2020

Robert E Widdop

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15 March 2020

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Claudia A McCarthy

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15 March 2020

Alyson A Miller

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15 March 2020

Anders Hallberg

4

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15 March 2020

Mathias Alterman

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15 March 2020

Jennifer K Callaway

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15 March 2020

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21 April 2014

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15 March 2020

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15 March 2020

9

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15 March 2020

4

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15 March 2020

e95762

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15 March 2020

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Creative Commons Attribution 4.0 International

21 April 2014

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April 2022 Public Data File from Crossref

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International union of pharmacology. XXIII. The angiotensin II receptors

1 reference

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19 March 2017

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

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7 April 2017

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

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7 April 2017

AT1 receptor antagonism is proangiogenic in the brain: BDNF a novel mediator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994132

29 September 2017

Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994132

29 September 2017

Repertoire of microglial and macrophage responses after spinal cord injury

1 reference

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29 September 2017

Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994132

29 September 2017

AT2 receptors: functional relevance in cardiovascular disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994132

29 September 2017

Role of microglia in the central nervous system's immune response

1 reference

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29 September 2017

Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994132

29 September 2017

Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994132

29 September 2017

Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification

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29 September 2017

Macrophages and Microglia Produce Local Trophic Gradients That Stimulate Axonal Sprouting Toward but Not beyond the Wound Edge

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29 September 2017

Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994132

3 June 2018

Prevention of Heart Failure in Patients in the Heart Outcomes Prevention Evaluation (HOPE) Study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Effects of a perindopril-based blood pressure-lowering regimen on the risk of recurrent stroke according to stroke subtype and medical history: the PROGRESS Trial

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Neuroprotective effects of candesartan against cerebral ischemia in spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Chronic pretreatment with candesartan improves recovery from focal cerebral ischaemia in rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Protection against ischemia and improvement of cerebral blood flow in genetically hypertensive rats by chronic pretreatment with an angiotensin II AT1 antagonist

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Protective effect of candesartan in experimental ischemic stroke in the rat mediated by AT2 and AT4 receptors

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Angiotensin II type 2 receptor stimulation initiated after stroke causes neuroprotection in conscious rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Angiotensin AT2 receptor stimulation causes neuroprotection in a conscious rat model of stroke.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage

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21 January 2018

Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats.

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21 January 2018

Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Candesartan but not ramipril pretreatment improves outcome after stroke and stimulates neurotrophin BNDF/TrkB system in rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095762

21 January 2018

Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury

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21 January 2018

Angiotensin II increases neuronal delayed rectifier K(+) current: role of 12-lipoxygenase metabolites of arachidonic acid

1 reference

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12 December 2020

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A novel, rapid, computerized method for quantitation of neuronal damage in a rat model of stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/24752645

12 December 2020

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inferred from PubMed ID database lookup

Phagocytic response in photochemically induced infarction of rat cerebral cortex. The role of resident microglia

1 reference

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Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24752645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/24752645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0095762

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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15 March 2020

2014PLoSO...995762M

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Consolidated OpenCitations Corpus – April 2017

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2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752645%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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15 March 2020

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