DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility (Q28511686)

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English	DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility	scientific journal article

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scholarly article

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PubMed publication ID

25 January 2017

DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility (English)

1 reference

PubMed publication ID

25 January 2017

phosphorylation

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Dual specificity phosphatase 6

1 reference

GOA release 2020-03-11

author name string

Marjorie Maillet

1

1 reference

PubMed publication ID

25 January 2017

Nicole H. Purcell

2

1 reference

PubMed publication ID

25 January 2017

Michelle A. Sargent

3

1 reference

PubMed publication ID

25 January 2017

Allen J. York

4

1 reference

PubMed publication ID

25 January 2017

Orlando F. Bueno

5

1 reference

PubMed publication ID

25 January 2017

Jeffery D. Molkentin

6

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PubMed publication ID

25 January 2017

language of work or name

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publication date

7 November 2008

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PubMed publication ID

25 January 2017

Journal of Biological Chemistry

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PubMed publication ID

25 January 2017

283

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PubMed publication ID

25 January 2017

45

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PubMed publication ID

25 January 2017

31246–31255

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PubMed publication ID

25 January 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2576531/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2576531/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

19 March 2017

B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

19 March 2017

Essential role for ERK2 mitogen-activated protein kinase in placental development

1 reference

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19 March 2017

Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation

1 reference

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19 March 2017

Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

1 reference

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Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

1 reference

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19 March 2017

MAP kinase phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

19 March 2017

bcl-2 overexpression promotes myocyte proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

19 March 2017

Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival

1 reference

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19 March 2017

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

1 reference

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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

1 reference

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19 March 2017

MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

19 March 2017

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

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7 April 2017

Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study

1 reference

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7 April 2017

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

1 reference

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7 April 2017

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

The MEK/ERK cascade: from signaling specificity to diverse functions

1 reference

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Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy

1 reference

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29 September 2017

Structural basis of docking interactions between ERK2 and MAP kinase phosphatase 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

1 reference

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29 September 2017

Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2.

1 reference

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29 September 2017

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

1 reference

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29 September 2017

Dual specificity phosphatases: a gene family for control of MAP kinase function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Organization and regulation of mitogen-activated protein kinase signaling pathways

1 reference

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29 September 2017

Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

The epidemiology of heart failure: the Framingham Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Cardiac Muscle Cell Proliferation and Cell Differentiation in Vivo and in Vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

29 September 2017

Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3.

1 reference

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2 June 2018

Protein phosphatase 2A-mediated cross-talk between p38 MAPK and ERK in apoptosis of cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

2 June 2018

A Bipartite Mechanism for ERK2 Recognition by Its Cognate Regulators and Substrates

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2 June 2018

ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes.

1 reference

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27 November 2018

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

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The role of erk1 and erk2 in multiple stages of T cell development

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27 November 2018

Genetic inhibition or activation of JNK1/2 protects the myocardium from ischemia-reperfusion-induced cell death in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

27 November 2018

Targeted expression of calmodulin increases ventricular cardiomyocyte proliferation and deoxyribonucleic acid synthesis during mouse development.

1 reference

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27 November 2018

P38 mitogen-activated protein kinase dephosphorylation is regulated by protein phosphatase 2A in human platelets activated by collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

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The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

27 November 2018

The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576531

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IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress

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27 November 2018

Mapping ERK2-MKP3 binding interfaces by hydrogen/deuterium exchange mass spectrometry

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https://pubmed.ncbi.nlm.nih.gov/18753132

12 December 2020

based on heuristic

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Mechanism of mitogen-activated protein kinase phosphatase-3 activation by ERK2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753132

12 December 2020

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Mechanistic basis for catalytic activation of mitogen-activated protein kinase phosphatase 3 by extracellular signal-regulated kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18753132

12 December 2020

based on heuristic

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