Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism (Q28508765)

24 January 2017

title

Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism (English)

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Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

24 January 2017

main subject

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RAR-related orphan receptor gamma

GOA release 2020-03-11

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RAR-related orphan receptor alpha

GOA release 2020-03-11

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GOA release 2020-03-11

Chang Liu

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24 January 2017

Siming Li

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24 January 2017

Tiecheng Liu

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24 January 2017

Jimo Borjigin

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24 January 2017

Jiandie D. Lin

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24 January 2017

language of work or name

English

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publication date

24 May 2007

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24 January 2017

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24 January 2017

volume

447

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24 January 2017

issue

7143

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24 January 2017

page(s)

477–481

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Metabolism and the control of circadian rhythms

24 January 2017

cites work

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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

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Metabolic control through the PGC-1 family of transcription coactivators

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Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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Coordinated transcription of key pathways in the mouse by the circadian clock

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Extensive and divergent circadian gene expression in liver and heart

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A transcription factor response element for gene expression during circadian night

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Interplay of circadian clocks and metabolic rhythms

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BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

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The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

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A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

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Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock

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RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR

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Circadian regulator CLOCK is a histone acetyltransferase

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PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

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A serum shock induces circadian gene expression in mammalian tissue culture cells

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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7 January 2021

Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

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