IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9 (Q28507728)

24 January 2017

title

IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9 (English)

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Interferon regulatory factor 7

24 January 2017

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Inhibitor of nuclear factor kappa-B kinase subunit alpha

GOA release 2020-03-11

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ORCID Public Data File 2021

GOA release 2020-03-11

Shizuo Akira

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Osamu Ohara

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Katsuaki Hoshino

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24 January 2017

Takahiro Sugiyama

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24 January 2017

Mitsuru Matsumoto

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24 January 2017

Takashi Tanaka

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24 January 2017

Masuyoshi Saito

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24 January 2017

Hiroaki Hemmi

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24 January 2017

Tsuneyasu Kaisho

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24 January 2017

language of work or name

English

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publication date

13 April 2006

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24 January 2017

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24 January 2017

volume

440

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24 January 2017

issue

7086

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24 January 2017

page(s)

949–953

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Toll-like receptors and innate immunity

24 January 2017

cites work

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

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Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

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Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

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Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

21 January 2018

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IRF-7 is the master regulator of type-I interferon-dependent immune responses

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

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Signaling to NF-kappaB

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The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

21 January 2018

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Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection

21 January 2018

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Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

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IkappaB kinase alpha is essential for mature B cell development and function

21 January 2018

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

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Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

21 January 2018

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Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

21 January 2018

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Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells

21 January 2018

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The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets

21 January 2018

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Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

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Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways

21 January 2018

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Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

1 reference

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