A biochemical function for attractin in agouti-induced pigmentation and obesity (Q28505368)

24 January 2017

title

A biochemical function for attractin in agouti-induced pigmentation and obesity (English)

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24 January 2017

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GOA release 2020-03-11

Nonagouti

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GOA release 2020-03-11

L. He

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24 January 2017

T. M. Gunn

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24 January 2017

D. M. Bouley

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24 January 2017

X. Y. Lu

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24 January 2017

S. J. Watson

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24 January 2017

S. F. Schlossman

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24 January 2017

J. S. Duke-Cohan

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24 January 2017

G. S. Barsh

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24 January 2017

language of work or name

English

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publication date

1 January 2001

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24 January 2017

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24 January 2017

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24 January 2017

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24 January 2017

page(s)

40–47

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Molecular and developmental genetics of mouse coat color

24 January 2017

cites work

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7 January 2021

Agouti structure and function: characterization of a potent alpha-melanocyte stimulating hormone receptor antagonist

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Central nervous system control of food intake

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Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice

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Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

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Biochemical, biophysical, and pharmacological characterization of bacterially expressed human agouti-related protein

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Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

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Effects of recombinant agouti-signaling protein on melanocortin action

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Characterization of Agouti-related protein binding to melanocortin receptors

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Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

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Targeted disruption of the melanocortin-4 receptor results in obesity in mice

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Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions

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7 January 2021

The mouse mahogany locus encodes a transmembrane form of human attractin

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The mahogany protein is a receptor involved in suppression of obesity

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Secreted and membrane attractin result from alternative splicing of the human ATRN gene

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Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo

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Agouti and agouti-related protein: analogies and contrasts

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Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti

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Distribution of Mahogany/Attractin mRNA in the rat central nervous system.

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Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

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Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo.

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Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants

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Mutations in the carboxyl terminus of the agouti protein decrease agouti inhibition of ligand binding to the melanocortin receptors

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The mahogany mouse mutation: further links between pigmentation, obesity and the immune system.

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Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display

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The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

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Widespread expression of Agouti-related protein (AGRP) in the chicken: a possible involvement of AGRP in regulating peripheral melanocortin systems in the chicken

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Neuropilin is a receptor for the axonal chemorepellent Semaphorin III

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Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

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Infection of eucaryotic cells by helper-independent recombinant adenoviruses: early region 1 is not obligatory for integration of viral DNA

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A human beta-actin expression vector system directs high-level accumulation of antisense transcripts

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A Novel Form of Dipeptidylpeptidase IV Found in Human Serum

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Down-regulation of melanocortin receptor signaling mediated by the amino terminus of Agouti protein in Xenopus melanophores

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Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system

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