Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity (Q28492135)

24 January 2017

title

Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity (English)

1 reference

24 January 2017

Keith A. Stubbs

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Rebecca J. Dennis

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24 January 2017

Edward J. Taylor

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24 January 2017

Matthew S. Macauley

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24 January 2017

Johan P. Turkenburg

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24 January 2017

Samuel J. Hart

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24 January 2017

Gary N. Black

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24 January 2017

David J. Vocadlo

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24 January 2017

Gideon J. Davies

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24 January 2017

publication date

1 April 2006

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Nature Structural & Molecular Biology

24 January 2017

published in

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24 January 2017

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DOI.org query endpoint

https://doi.org/10.1017%2FS0373463314000502

24 January 2017

9 April 2017

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24 January 2017

27 March 2017

https://doi.org/10.1038%2FHDY.2009.109

page(s)

365–371

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DOI.org query endpoint

O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

24 January 2017

cites work

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O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats

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Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

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Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

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The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

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Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities

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A Genomic View of the Human-Bacteroides thetaiotaomicron Symbiosis

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NAG-thiazoline, An N -Acetyl-β-hexosaminidase Inhibitor That Implicates Acetamido Participation

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Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease

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Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase

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Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

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Stereochemistry of chitin hydrolysis by a plant chitinase/lysozyme and X-ray structure of a complex with allosamidin: evidence for substrate assisted catalysis

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Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease

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Refinement of macromolecular structures by the maximum-likelihood method

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Automated protein model building combined with iterative structure refinement

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

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Substructure solution with SHELXD

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Glycan foraging in vivo by an intestine-adapted bacterial symbiont

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Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: alternative glycosylation/phosphorylation of THR-58, a known mutational hot spot of c-Myc in lymphomas, is regulated by mitogens

21 April 2017

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Alternative O-glycosylation/O-phosphorylation of the murine estrogen receptor beta.

21 January 2018

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Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line

21 January 2018

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Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway

21 January 2018

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Cytoplasmic O-GlcNAc modification of the head domain and the KSP repeat motif of the neurofilament protein neurofilament-H

21 January 2018

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O-GlcNAc modification is an endogenous inhibitor of the proteasome

21 January 2018

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A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans

21 January 2018

1 reference

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

21 January 2018

1 reference

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha

21 January 2018

1 reference

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

21 January 2018

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A classification of glycosyl hydrolases based on amino acid sequence similarities

21 January 2018

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Galactose recognition by the carbohydrate-binding module of a bacterial sialidase

21 January 2018

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O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

21 January 2018

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O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis

21 January 2018

1 reference

Crystal structure of hyaluronidase, a major allergen of bee venom

21 January 2018

1 reference

Identification of Asp174 and Asp175 as the key catalytic residues of human O-GlcNAcase by functional analysis of site-directed mutants

21 January 2018

1 reference

A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase.

21 January 2018

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Genotoxicity of streptozotocin

21 January 2018

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Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis

21 January 2018

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The CCP4 suite: programs for protein crystallography

21 January 2018

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Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase

21 January 2018

1 reference