Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A (Q28483362)

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13 February 2020

title

Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A (English)

1 reference

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13 February 2020

main subject

hemophilia

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Coagulation factor VIII

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0 references

1 reference

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13 February 2020

1 reference

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13 February 2020

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13 February 2020

Stefanie D Roth

1 reference

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13 February 2020

Peter Milanov

1 reference

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13 February 2020

Daniela Abriss

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13 February 2020

Christopher Ungerer

1 reference

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13 February 2020

Patricia Quade-Lyssy

1 reference

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13 February 2020

Erhard Seifried

1 reference

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13 February 2020

Torsten Tonn

1 reference

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13 February 2020

language of work or name

English

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publication date

4 September 2012

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13 February 2020

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volume

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issue

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13 February 2020

page(s)

e44505

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Creative Commons Attribution 4.0 International

13 February 2020

start time

4 September 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Two novel mutations in EGF-like domains of human factor IX dramatically impair intracellular processing and secretion

29 September 2017

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Confocal microscopy analysis of native, full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells

29 September 2017

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Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo

27 November 2018

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27 November 2018

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Factor IX variants improve gene therapy efficacy for hemophilia B.

27 November 2018

1 reference

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Sustained phenotypic correction of murine hemophilia A by in vivo gene therapy

27 November 2018

1 reference

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Biochemical, immunological, and in vivo functional characterization of B-domain-deleted factor VIII.

27 November 2018

1 reference

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Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

27 November 2018

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Mutagenesis of a potential immunoglobulin-binding protein-binding site enhances secretion of coagulation factor VIII

27 November 2018

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12 December 2020

A pilot clinical trial of oral sodium 4-phenylbutyrate (Buphenyl) in deltaF508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR function

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12 December 2020

Transgene loss and changes in the promoter methylation status as determinants for expression duration in nonviral gene transfer for factor IX

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12 December 2020

Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans

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12 December 2020

10.1371/JOURNAL.PONE.0044505

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22973456%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

ADS bibcode

2012PLoSO...744505R

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22973456%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22973456

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22973456%20AND%20SRC:MED&resulttype=core&format=json