Characterizing the network of drugs and their affected metabolic subpathways (Q28484558)

0 references

Desi Shang

0 references

Yan Wang

0 references

Jing Li

0 references

Junwei Han

0 references

Shuyuan Wang

0 references

Qianlan Yao

0 references

Yingying Wang

0 references

Yunpeng Zhang

0 references

Chunlong Zhang

0 references

Yanjun Xu

0 references

Wei Jiang

0 references

Xia Li

Creative Commons Attribution 4.0 International

0 references

language of work or name

English

0 references

publication date

2012

0 references

0 references

0 references

0 references

e47326

0 references

start time

24 October 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

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Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate

19 March 2017

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Drug discovery: Predicting promiscuity

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Network pharmacology: the next paradigm in drug discovery

19 March 2017

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19 March 2017

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19 March 2017

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From genomics to chemical genomics: new developments in KEGG

19 March 2017

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Network biology: understanding the cell's functional organization

19 March 2017

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Antipsychotic drugs differentially modulate apolipoprotein D in rat brain

19 March 2017

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A side effect resource to capture phenotypic effects of drugs

19 March 2017

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Network medicine: a network-based approach to human disease

7 April 2017

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

7 April 2017

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Drug target identification using side-effect similarity

7 April 2017

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7 April 2017

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Global mapping of pharmacological space

7 April 2017

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Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing.

7 April 2017

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The implications of relationships between human diseases and metabolic subpathways

29 September 2017

1 reference

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Sex Hormones, Metabolic Syndrome and Kidney

29 September 2017

1 reference

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Effect of Antibiotic Treatment on the Intestinal Metabolome

29 September 2017

1 reference

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A sub-pathway-based approach for identifying drug response principal network

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

MiRNA–miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features

29 September 2017

1 reference

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Network biology as a new approach to drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Influence of sex hormones on cancer progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Phospholipase A2 and arachidonic acid in Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Disease-aging network reveals significant roles of aging genes in connecting genetic diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Inhibition of thromboxane A2-induced arrhythmias and intracellular calcium changes in cardiac myocytes by blockade of the inositol trisphosphate pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

SubpathwayMiner: a software package for flexible identification of pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Network analyses in systems pharmacology

29 September 2017

1 reference

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Differential effects of steroids on the synthesis of polyunsaturated fatty acids by human neuroblastoma cells

29 September 2017

1 reference

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Definition, conservation and epigenetics of housekeeping and tissue-enriched genes

29 September 2017

1 reference

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Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis.

29 September 2017

1 reference

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Regulation of brain polyunsaturated fatty acid uptake and turnover

29 September 2017

1 reference

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Networking metabolites and diseases

29 September 2017

1 reference

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A global view of drug-therapy interactions

29 September 2017

1 reference

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Quantitative systems-level determinants of human genes targeted by successful drugs.

29 September 2017

1 reference

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Analysis of system structure-function relationships

29 September 2017

1 reference

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Clindamycin-induced acute cholestatic hepatitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Folate metabolism as a source of molecular targets for antimalarials.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Clinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Clindamycin and taste disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

The modular nature of genetic diseases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Systems biology, metabolic modelling and metabolomics in drug discovery and development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Analysis of drug-induced effect patterns to link structure and side effects of medicines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Identifying drug active pathways from gene networks estimated by gene expression data.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Pharmacogenetics of folate-related drug targets in cancer treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Elucidating mechanisms of drug-induced toxicity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Epidemiology, etiology, and natural treatment of seasonal affective disorder

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Functional cartography of complex metabolic networks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Hierarchical thinking in network biology: the unbiased modularization of biochemical networks.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Antiinflammatory and antiulcer activities of phytic acid in rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Metabolic networks: enzyme function and metabolite structure.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Predicting ADME properties and side effects: the BioPrint approach.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Tryptophan as a link between psychopathology and somatic states

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Human housekeeping genes are compact

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Myo-inositol-1-phosphate (MIP) synthase: a possible new target for antibipolar drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Pharmacogenetics and folate metabolism -- a promising direction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Activation of human CIC-2 Cl- channels: implications for cystic fibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

PI-3 kinase in signal transduction, cell transformation, and as a target for chemoprevention of cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Adrenal gland: chemically induced structural and functional changes in the cortex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Antazoline‐induced Immune Hemolytic Anemia, Hemoglobinuria, and Acute Renal Failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Mining metabolic networks for optimal drug targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by a Coptidis Rhizoma extract and protoberberine alkaloids

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Effect of anti-inflammatory and analgesic pyrazoles on arachidonic acid metabolism in isolated heart and gastric mucosa preparations.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Colon perforation with acute peritonitis after taking clindamycin and diclofenac following wisdom tooth removal

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

Hypersensitivity reaction to intravitreal clindamycin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

Calcium and neostigmine antagonize gentamicin, but augment clindamycin-induced tetanic fade in rat phrenic nerve-hemidiaphragm preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

Clinical significance of simultaneous determination of serum tryptophan and tyrosine in patients with lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

In vitro and ex vivo permeation studies of etodolac from hydrophilic gels and effect of terpenes as enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

Comparative hepatic toxicity: prechronic/chronic liver toxicity in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

Dissection of human MiRNA regulatory influence to subpathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047326

Identification of pathways involved in paclitaxel activity in cervical cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Network analysis of adverse drug interactions

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Effect of histamine receptor antagonists on aminophylline-induced seizures and lethality in mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480395

Vascular injury following accidental intra-arterial injection of clindamycin: adverse drug reaction report

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23112813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23112813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Drug-induced gynecomastia]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23112813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0047326

1 reference

ADS bibcode

2012PLoSO...747326L

0 references

1 reference

1 reference

PubMed publication ID

23112813

1 reference