Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110 (Q28391904)

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Joseph M Baisden

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Scott A Weed

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Daniel C Flynn

Molecular and Cellular Biology

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language of work or name

English

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publication date

September 2004

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published in

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volume

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issue

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page(s)

7578-97

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cites work

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Podosomes: adhesion hot-spots of invasive cells

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Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway

29 September 2017

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The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases

29 September 2017

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The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphos

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Formation of a stable src-AFAP-110 complex through either an amino-terminal or a carboxy-terminal SH2-binding motif

29 September 2017

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Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity

29 September 2017

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29 September 2017

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The Sites of Phosphorylation by Protein Kinase C and an Intact SH2 Domain Are Required for the Enhanced Response to β-Adrenergic Agonists in Cells Overexpressing c-src

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Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

29 September 2017

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Increased protein kinase C alpha expression in human colonic Caco-2 cells after insertion of human Ha-ras or polyoma virus middle T oncogenes.

2 June 2018

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Protein kinase C phosphorylates pp60src at a novel site.

2 June 2018

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Site-specific increased phosphorylation of pp60v-src after treatment of RSV-transformed cells with a tumor promoter.

2 June 2018

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pp60v-src association with the cytoskeleton induces actin reorganization without affecting polymerization status.

2 June 2018

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v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts

2 June 2018

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Localization of the viral and cellular Src kinases to perinuclear vesicles in fibroblasts

2 June 2018

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Protein kinase C delta induces Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha

2 June 2018

1 reference

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Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in a7r5 smooth muscle cells

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

Cytoskeletal architecture in mouse lung epithelial cells is regulated by protein-kinase C-alpha and calpain II

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15314167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential activation of protein kinase C isozymes by phorbol ester and collagen in human skin microvascular endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15314167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.24.17.7578-7597.2004

1 reference

release_m4ylrdkb45advobh6zjcvua27i

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

15314167

1 reference