Soluble epoxide hydrolase: a novel therapeutic target in stroke (Q28388145)

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Ruediger Noppens

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Marjorie Grafe

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Hsing-Ju Tsai

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John R Falck

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Nabil J Alkayed

Journal of Cerebral Blood Flow & Metabolism

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language of work or name

English

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publication date

December 2007

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published in

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volume

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issue

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page(s)

1931-40

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cites work

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The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke

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Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow

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Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

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Epoxygenase products of arachidonic acid are endogenous constituents of the hypothalamus involved in D2 receptor-mediated, dopamine-induced release of somatostatin

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Improved radiolabeled substrates for soluble epoxide hydrolase

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The coronary endothelium-derived hyperpolarizing factor (EDHF) stimulates multiple signalling pathways and proliferation in vascular cells.

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Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility

21 January 2018

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Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids

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Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes

21 January 2018

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Structural refinement of inhibitors of urea-based soluble epoxide hydrolases

21 January 2018

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11,12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27Kip1.

21 January 2018

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Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high-performance liquid chromatography with electrospray tandem mass spectrometry

21 January 2018

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Vascular localization of soluble epoxide hydrolase in the human kidney

21 January 2018

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Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.

21 January 2018

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Preparation of lipide extracts from brain tissue.

27 November 2018

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Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes

27 November 2018

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Mechanism and signal transduction of 14 (R), 15 (S)-epoxyeicosatrienoic acid (14,15-EET) binding in guinea pig monocytes

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17440491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective inhibition of arachidonic acid epoxidation in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17440491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen and Bcl-2: gene induction and effect of transgene in experimental stroke

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17440491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.JCBFM.9600494

1 reference

1 reference

1 reference

PubMed publication ID

17440491

1 reference