The tumor microenvironment and strategies to improve drug distribution (Q28384148)

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English	The tumor microenvironment and strategies to improve drug distribution	scientific article

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title

The tumor microenvironment and strategies to improve drug distribution (English)

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author

Ian F. Tannock

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4

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Ian F Tannock

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author name string

Jasdeep K Saggar

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1

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Man Yu

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2

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Qian Tan

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3

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language of work or name

English

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publication date

2013

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published in

Frontiers in Oncology

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stated in

Crossref

volume

3

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page(s)

154

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cites work

Mitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitination

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

20 March 2017

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

20 March 2017

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

7 April 2017

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

7 April 2017

Targeting hypoxia in cancer therapy

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

7 April 2017

Drug resistance and the solid tumor microenvironment

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

7 April 2017

Drug penetration in solid tumours

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

7 April 2017

High interstitial fluid pressure - an obstacle in cancer therapy

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

7 April 2017

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

7 April 2017

Use of molecular biomarkers to quantify the spatial distribution of effects of anticancer drugs in solid tumors

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Quantitative immunohistochemistry for evaluating the distribution of Ki67 and other biomarkers in tumor sections and use of the method to study repopulation in xenografts after treatment with paclitaxel

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Selective tumor hypoxia targeting by hypoxia-activated prodrug TH-302 inhibits tumor growth in preclinical models of cancer.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

The role of autophagy in cancer: therapeutic implications

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Intravital microscopy in window chambers: a unique tool to study tumor angiogenesis and delivery of nanoparticles

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

The distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab within solid tumors

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Hypoxia-activated prodrugs in cancer therapy: progress to the clinic

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

The pK(a) Distribution of Drugs: Application to Drug Discovery

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Tumor interstitial fluid pressure as an early-response marker for anticancer therapeutics

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Interstitial fluid pressure in tumors: therapeutic barrier and biomarker of angiogenesis.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Hypoxia inducible factor-1 independent pathways in tumor angiogenesis.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Pharmacokinetic variability of anticancer agents

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Vascular architecture, hypoxia, and proliferation in first-generation xenografts of human head-and-neck squamous cell carcinomas

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Tumor transport physiology: implications for imaging and imaging-guided therapy

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Doxorubicin gradients in human breast cancer.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

29 September 2017

Inhibition of endosomal sequestration of basic anticancer drugs: influence on cytotoxicity and tissue penetration

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

2 June 2018

Growth of mammalian multicellular tumor spheroids.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

2 June 2018

Tumour cell proliferation in relation to the vasculature

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

2 June 2018

Autophagy and cancer

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

27 November 2018

The distribution of the anticancer drug Doxorubicin in relation to blood vessels in solid tumors.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

27 November 2018

Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

27 November 2018

Selective induction of apoptosis with proton pump inhibitor in gastric cancer cells

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

27 November 2018

Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

27 November 2018

Limited penetration of anticancer drugs through tumor tissue: a potential cause of resistance of solid tumors to chemotherapy

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

27 November 2018

Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677151

retrieved

27 November 2018

Beclin-1 and LC3A expression in cutaneous malignant melanomas: a biphasic survival pattern for beclin-1

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor hypoxia, p53, and prognosis in cervical cancers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of paclitaxel penetration and accumulation in human solid tumor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of systemically administered [3H]-paclitaxel in rats: a quantitative autoradiographic study

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Light-chain 3A autophagic activity and prognostic significance in non-small cell lung carcinomas

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal pharmacodynamics of omeprazole. A survey of its pharmacological properties in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23772420

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.3389/FONC.2013.00154

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3509854

OpenCitations bibliographic resource ID

3509854

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3509854

PMC publication ID

3677151

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3509854

PubMed publication ID

23772420

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3509854

ResearchGate publication ID

239078019

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