Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT (Q28374498)

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English	Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT	scientific article

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scholarly article

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Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT (English)

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Vernon E Walker

9

object named as

V E Walker

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Miriam C. Poirier

5

object named as

M C Poirier

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2

object named as

O A Olivero

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author name string

H E Sussman

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Q Meng

3

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S M Pietras

4

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J P O'Neill

6

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B A Finette

7

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M J Bauer

8

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language of work or name

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publication date

19 October 1999

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Mutation Research

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429

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2

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249-59

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Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

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Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats

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Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326

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Clinical pharmacokinetics of zidovudine. An update

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Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys

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Mutation assay at the thymidine kinase locus in diploid human lymphoblasts

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Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families

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Gene mutations with characteristic deletions in cord blood T lymphocytes associated with passive maternal exposure to tobacco smoke

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Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification

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3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8.

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Intracellular metabolism of 3'-azidothymidine in isolated human peripheral blood mononuclear cells

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Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero

1 reference

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

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Regulation of lymphocyte survival by the bcl-2 gene family

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Apoptosis in leukocytes.

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p53, mutation frequency and apoptosis in the murine small intestine

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Molecular analysis of hypoxanthine phosphoribosyltransferase gene deletions induced by alpha- and X-radiation in human lymphoblastoid cells

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Spectra of Spontaneous and X-Ray-Induced Mutations at the hprt Locus in Related Human Lymphoblast Cell Lines That Express Wild-Type or Mutant p53

1 reference

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7 January 2021

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10.1016/S0027-5107(99)00111-6

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